P-Anisaldehyde 4-methoxybenzaldehyde

H.53) Benzaldehyde, 4-methoxy-, 4-methoxybenzaldehyde, p-anisaldehyde, p-formylanisole 123-ll-5] FEMA 2670... 

Practical-grade 4-cthoxy-3-methoxybenzaldehyde (4-ethoxy-m-anisaldehyde) was obtained by the submitters from MC and B Manufacturing Chemists and by the checkers from Aldrich Chemical Company, Inc. This material was purified by distillation (b.p. 125-135°/0.1 mm.), followed by one recrystallization from cyclohexane (100 ml./lO g. crude solid). Colorless crystals, m.p. 60-62°, wrere obtained after filtration and vacuum drying. Purification of 20 g. of the commercial material gave about 15 g. of recrystallized product. 

Synonyms m-Anisaldehyde Vanillic aldehyde Lioxin 3-Methoxy-4-hydroxybenzaldehyde p-Hydroxy-m-methoxybenzaldehyde Lioxin Vanillaldehyde Vanillic aldehyde 2-Methoxy-4-formylphenol 3-Methoxy-4-hydroxybenzalde-hyde Vanilla Protocatechualdehyde, methyl- Zimco p-Vanillin Methylprotcatechuic aldehyde Methylprotocatechuic aldehyde Chemical/Pharmaceutical/Other Class Essential oil... 

AI3-00223 Anisaldehyde /tnisic aldehyde Aubepine Benzaldehyde, 4-methoxy- Caswell No. 051E CCRIS 821 Crategine EINECS 204-602-6 FEMA No. 2670 Formylanisole, p- HSDB 2641 4-Methoxybenzaldehyde NSC 5590 Obepin. Used in perfumery. Liquid mp = 0° bp = 248°, bpi2 = 134° d = 1,119 km 273 nm (MeOH) insoluble in H2O, soluble in CeHe, very soluble in MezCO, CHCI3, freely soluble In EtOH, EtzO LDsO (rat orl) = 1510 mg/kg. 

Synonyms Anisaldehyde Anisic aldehyde p-Anisic aldehyde Aubepine 4-Methoxybenzaldehyde... 

Choose one of three aldehydes for this experiment piperonaldehyde (solid), 3-nitrobenzaldehyde (solid), or p-anisaldehyde (liquid). Place 0.150 g of piperonaldehyde (3,4-methylenedioxybenzaldehyde, MW = 150.1) or 0.151 g of 3-nitrobenzaldehyde (MW = 151.1) into a 5-mL conical vial. Alternatively, transfer 0.13 mL of p-anisaldehyde (4-methoxybenzaldehyde, MW = 136.2) to a fared conical vial and reweigh the vial to determine the weight of material transferred. 

You will perform the crossed-aldol condensation of acetophenone (21) with p-anisaldehyde (4-methoxybenzaldehyde, 23) to give frans-p-anisalacetophenone (25) according to the sequence outlined in Scheme 18.4. For steric and electronic reasons, the enolate ion 22 reacts preferentially with 23 rather than 21, leading to the aldol 24. This product then dehydrates in the presence of base, in the manner outlined in Equation 18.11, to yield the condensation product 25. Part of the thermodynamic driving force for this dehydration is associated with forming a new carbon-carbon ir-bond that is conjugated with the aromatic ring as well as with the... 

Methoxybenzaldehyde (or p-anisaldehyde) is obtained by the selective oxidation in organic-free water suspensions of home-prepared Ti02, at room temperature with a yield of 41.5 %mol. The by-products are traces of 4-methoxybenzoic acid, open ring products, and CO2 [3]. 

Anisaldehyde (p-methoxybenzaldehyde). Use the apparatus described for fi-resorcylaldehyde. Place 30 g (30 ml, 0.28 mol) of anisole, 75 ml of sodium-dried benzene (CAUTION) and 52 g (0.44 mol) of powdered zinc cyanide in the flask. Cool the mixture in a bath of cold water, start the stirrer and pass in a rapid stream of hydrogen chloride for 1 hour. Remove the gas inlet tube, and without stopping the stirrer, add 45 g of finely powdered anhydrous aluminium chloride slowly. Replace the gas inlet and pass in a slow steam of hydrogen chloride while heating the mixture at 40-45 °C for 3-4 hours. Allow... 

Anisaldehyde or Methoxybenzaldehyde, HjCO.QH4.CHO, mw 136.14 Note Although the name "anisaldehyde previously was reserved for the "p-methoxybenzal-dehydi , current nomenclature extends the term "anisaldehyde to all methoxybenzaldehydes, provided it is indicated which of the isomers is being described. Thus there will be o- (or 2-), m- (or 3-) and p- (or 4-) anisaldehydes These compds are described as "methoxybenzaldehydes in Beil 8, 43,59.67,(519.525, 529) [40,53,64]... 

Tetrabromo-o-quinone o-N aphthoquinone 4-Chloro-l,2-Naphthoquinone 6-Bromo-l, 2-Naphthoquinone p-Tolualdehyde 14 1, anisaldehyde 14S) Acetaldehyde 8) Acetaldehyde , />-nitrobenzaldehyde 8> Benzaldehyde 1° ), m-tolualdehyde 1 ), p-tolualdehyde 10 ), o-methoxybenzaldehyde 10 1, anisaldehyde 106>, o-chlorobenzaldc-hyde 4 1... 

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