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Methoxy-methyl-naphthaleneacetic acid

Chemical Name (+)-6-methoxy-a-methyl-2-naphthaleneacetic acid Common Name d-2-(6-methoxy-2-naphthyl)propionic acid Structural Formula ... [Pg.1059]

CN (S)-6-methoxy-a-methyl-2-naphthaleneacetic acid sodium salt... [Pg.1399]

A number of drugs have been successfully separated using MIPs. Naproxen , (S)-6-methoxy-a-methyl-2-naphthaleneacetic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that is administered as the S enantiomer. Naproxen (structure 16.20) will be used to illustrate the MIP sequence. Naproxen has both polar and nonpolar domains. It also has a fused-ring aromatic site. [Pg.509]

NAPHTHALENEACETIC ACID, 6-METHOXY-alnh -METHYL-, SODIUM SALT,... [Pg.141]

Goto et al. (67) synthesized the sucdnimidyl ester [14] of (—)- -methoxy-a-methyl-l-naphthaleneacetic acid for the normal-phase LC resolution of chiral amines. The reagent permitted the determination of the enantiomers of an amphetamine derivative in blood plasma after administration of racemic drug to rabbits. With detection at 280 nm, the lower limit of sensitivity was 5 ng/mL for each enantiomer (67). Several chiral acids from the "profen" group of nonsteroidal antiinflammatory drugs have been adapted as CDAs. One of these, naproxen, [15], is the S enantiomer and is commercially available as the resolved acid several of these acids have the advantage of providing fluorescent derivatives (68,69). [Pg.77]

It has now been discovered that this metabolite, when administered to laboratory animals in a standard pharmacological assay for analgesia (see exemplification), produces a pain-relieving effect which is merely equivalent to that of naproxen (6-Methoxy-a-methyl-2-naphthaleneacetic acid), a popular analgesic and anti-inflammatory agent in use today. Thus, the therapeutic effects of the Al-THC-7-oic-acid metabolite can be separated from the psychoactive effects of THC, the parent substance. [Pg.93]

S)-(+) Naproxen sodium [2-Naphthaleneacetic acid, (+)-6-methoxy-a-methyl-, sodium salt] Active as an analgesic, antipyretic and anti-inflammatory... [Pg.52]

Naproxen, (S)-6-Methoxy-a-methyl-2-naphthaleneacetic acid, is a popular anti-inflammatory, analgesic and antipyretic drug which is also used in veterinary medicine largely for its anti-inflammatory properties. Its structure is as follows ... [Pg.331]

Methoxy-(X-methyl-2-naphthaleneacetic acid, 9CI, SCI. 2-(6-Methoxy-2-naphthyl)propanoic acid. Naprosyn. Methoxypropriocin. Equiproxen. Numerous proprietary names [23981-80-8]... [Pg.721]

See other pages where Methoxy-methyl-naphthaleneacetic acid is mentioned: [Pg.964]    [Pg.1657]    [Pg.2397]    [Pg.964]    [Pg.759]    [Pg.348]    [Pg.10]    [Pg.2488]    [Pg.551]    [Pg.546]    [Pg.37]    [Pg.539]    [Pg.550]    [Pg.663]    [Pg.1035]    [Pg.1035]   
See also in sourсe #XX -- [ Pg.14 ]



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