Mestinon - Pyridostigmine bromide

Mestinon pyridostigmine bromide, mestranol [ban, inn, usan] (CB 8027 EE3ME L 33355 RS 1044) is a synthetic steroid oestrogen, a constituent in many combined oral CONTRACEPTIVES, and also used in oral HRT. mesulergino [inn] is an ergoline amine derivative, a (S-HTsc) 5-HYDROXYTRYPtAMINE RECEPTOR ANTAGONIST and DOPAMINE RECEPTOR ANTAGONIST, mesulfen mesulphen. 

The pharmacologic treatment of myasthenia gravis is based on increasing the amount of available acetylcholine by use of oral cholinesterase inhibitors such as neostigmine or pyridostigmine. Pyridostigmine bromide (Mestinon) is used most often and effectively relieves myasthenic symptoms in small muscles innervated by cranial nerves, particularly those involved in ptosis. 

Connon Name Pyridostigmine bromide Common Name Mestinon Chemical Type Carbamate Tox Num A014... 

Pyridostigmine Bromide. 3-[ (Dimethyiamino)-carbonyl]oxy]-l-mtthytpyridiniuni bromide 3-hydroxy-1-metkylpyridinium bromide dimethylcarbamate 1-methyl-3-hydroxy pyridinium bromide dimethylcarbamate 3-(dimeth-ylcarbamyloxy)-l -methylpyridinium bromide Rd 1-5130 Mestinon Bromide Kalymin Regonol. C,Hl3BrN.O, mol wt 261.14. C 41.39%, H 5.02%, Br 30.60%, N iO.73%, O 12.25%. Prepn Urban, U.S, pat. 2.572,579 (1951 to Hoffmann-La Roche). 

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