Mesenchymal hamartoma

R. Maresch described hamartoma as a cystic tumour structure in 1903 it was termed mesenchymal hamartoma by H.A. Edmondson in 1956. 

Cook, J.R., Pfeifer, J.D., Dehner, L.R Mesenchymal hamartoma of the hver in the adult Anociation with distinct clinical features and histological changes. Hum. Pathol. 2002 33 893-898... 

Lack, E.E. Mesenchymal hamartoma of the hver. A clinical and pathological study of nine cases. Amer. J. Pediatr. Hematof/Oncol. 1986 8 91 -98... 

Mesenchymal hamartomas are considered to be a developmental anomaly more than true neoplasm. A total of 75% of cases are located in the right lobe of the liver. Histologically MHR arise from the mesenchyma of the portal tract and will have connective tissue, blood vessels, lymphatic spaces, bile ducts and normal hepatocytes (Konez et al. 2001 Cetin et al. 2002). 

Mesenchymal hamartoma of the liver (MHL) is another benign neoplasm in children. Boys are slightly more affected than girls. It is very unusual to find an MHL after 5 years of age. The lesion usually has a good prognosis (Ramirez-Garredo et al. 2003 Yen et al. 2003). 

Fig. 4.7a-d. Mesenchymal hamartoma, a Plain film suggest hepatomegaly no ascites, b T2 MR image depicts a large cystic lesion with septations. c,d Tl MR confirms the predominantly cystic mesenchymal hamartoma... 

Cetin M, Demirpolat G, Elmas N et al (2002) Stromal predominant type mesenchymal hamartoma of liver CT and MR features. Comput Med Imaging Graph 26 167-169... 

Ramirez-Garredo F, De Dios LopezGonzalez-Garrido J, Ruiz-Lopez M-J et al (2003) Prenatal and postnatal imaging of an hepatic mesenchymal hamartoma. Eur J Pediatr 162 57-58... 

Yen J-B, Kong MS, Lin JN (2003) Hepatic mesenchymal hamartoma. J Paediatr Child Health 39 632-634... 

These lesions include mesenchymal hamartoma, infantile hemangioma angiomyolipoma, inflammatory pseudotumor pseudolipoma, isolated hepatic... 

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