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Membranous glomerulonephritis mercury exposure

Over the past decade there has, as result of experimental studies, been a growing appreciation that mercury may exert an effect on the immune system. As summarized by Silbergeld and Devine [72], mercury has at least two types of effects on the immune system. First, mercury induces autoimmunity to renal basement membrane proteins, causing mercury-induced glomerulonephritis in certain strains of mice and rats. Secondly, mercury exposure impairs cell-mediated and humoral immunity by affecting Thl and Th2 responses, which in turn impairs the body s ability to effectively... [Pg.817]

Tubbs R, Gordon D, Gephardt N, et al. 1982. Membranous glomerulonephritis associated with industrial mercury exposure—study of pathogenic mechanisms. Am J Clin Pathol 77 409-413. [Pg.651]

Tubbs, R.R., G.N. Gephardt, J.T. McMahon, M.C. Pohl, D.G. Vidt, S.A. Barenberg, and R. Valenzuela. 1982. Membranous glomerulonephritis associated with industrial mercury exposure. Study of pathogenetic mechanisms. Am. J. Clin. Pathol. 77(4) 409-13. [Pg.267]

See other pages where Membranous glomerulonephritis mercury exposure is mentioned: [Pg.539]    [Pg.568]    [Pg.1618]    [Pg.539]   
See also in sourсe #XX -- [ Pg.817 , Pg.819 ]

See also in sourсe #XX -- [ Pg.537 , Pg.539 ]



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