Membrane heparin-immobilized

The chitosan-heparin polyelectrolyte complex was covalently immobilized onto the surface of polyacrylonitrile membrane. The immobilization caused the water contact angle to decrease, thereby indicating an increase in hy-... 

In the previous papers(12,13), we reported on the vessel access type, i.e. tubular type, glucose sensor. It consisted of a glucose electrode system with a GOX enzyme immobilized Nylon membrane and a glucose semipermeable membrane, and a reference oxygen electrode system. The sensor could directly measure up to 700 mg/dl of BGL in an arterial blood stream when it was placed into an external A-V shunt. This sensor, however, has some problems such as thrombus during in vivo testing without heparin and clinical complexity associated with implanting the sensor in a blood stream. 

Asymmetric membranes, fabricated from poly(acrylonitrile-co-maleic acid) are immobilized with heparin and/or insulin in the presence of EDC to improve their surface... 

Different high molecular mass affinity ligands were successfully immobilized to monolithic disks.Monolithic disks with immobilized heparin and collagen were used for the purification of membrane proteins and annexins. The heparin unit was also used in the quality control of the preparation of the plasma proteins Antithrombin 111 and clotting Factor IX. Purification of IgG was successfully performed by immobilizing Protein... 

Cellulose acetate membrane [69] and cellulose fiber [70] were coated on PPy to remove gold iodide and Cr(VI), respectively. Ionic exchange was ascribe for the gold iodide removal and the reduction of Cr(VI) to Cr(III), followed by adsorption. A covalently immobilized heparin-PPy/ poly(ethylene glycol) methacrylate composite was also fabricated for biological applications to reduce the protein and thrombus formation [71]. 

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