Hypoglycemia meglitinides

Adverse reactions associated with the administration of tiie meglitinides include upper respiratory infection, headache, rhinitis, bronchitis, headache, back pain, and hypoglycemia... 

Meglitinides also increase pancreatic insulin release, and can cause hypoglycemia in overdose. 

While biguanides, alpha-glucosidase inhibitors, and glitazones are not likely to cause hypoglycemia after acute overdose, they may contribute to the hypoglycemic effects of sulfonylureas, meglitinides, or Insulin. 

Metabolisui The use of meglitinides has been evaluated in China in patients with type 2 diabetes, 433 of whom used nategli-nide and 436 repaglinide, mean age 55 years and BMI 25 kg/m. There was no statistically difference in the rates of adverse events, but the risk of an event was 0.59 times higher in those who took nateglinide the most common adverse event was hypoglycemia [67 ]. 

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