Medicinal chemistry orphan” receptors

Mohan, R. and Heyman, R.A. (2003) Orphan nuclear receptor modulators. Current Topics in Medicinal Chemistry, 3, 1637-1647. 

Zuercher, W.J., Gaillard, S., Orband-Miller, L.A., Chao, E.Y., Shearer, B.G., Jones, D.G., Miller, A.B., Collins, J.L. et al. (2005) Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRfJ and ERRy. Journal of Medicinal Chemistry, 48, 3107-3109. 

Willson, T.M., Brown, P.J., Sternbach, D.D. et al. (2000) The PPARs from orphan receptors to drug discovery. Journal of Medicinal Chemistry, 43, 527-550. 

---