Mechanical behavior biomaterials

Journal of Biomedical Materials Research Part A. Hoboken, NJ Wiley Interscience. ISSN 0021-9304. International, interdisciplinary focus with original contributions concerning studies of the preparation, performance, and evaluation of biomaterials the chemical, physical, toxicological, and mechanical behavior of materials in physiological environments and the response of blood and tissues to biomaterials. Peer-reviewed. 

Gomes, M. E., Ribeiro, A. S., Malafaya, P. B Reis, R. L., Cunha, A. M. (2001). A new approach based on injection moulding to produce biodegradable starchbased polymeric scaffolds morphology, mechanical and degradation behavior. Biomaterials, 22, 883-889. 

S.M. Kurtz, M.L. Villarraga, K. Zhao, A.A. Edidin, Static and fatigue mechanical behavior of bone cement with elevated barium sulfate content for treatment of vertebral compression fractures, Biomateri-afr26(2005) 3699-3712. 

From Edidin A.A., and S.M. Kurtz. 2000. The influence of mechanical behavior on the wear of four clinically relevant polymeric biomaterials in a hip simulator, j Arthroplasty 15 321-33 I. 

Edidin A.A., C.W. Jewett, K. Kwarteng, et al. 2000. Degradation of mechanical behavior in UHMWPE after natural and accelerated aging. Biomaterials 21 1451-1460. 

Kurtz S.M., C.M. Rimnac, L. Pruitt, et al. 2000. The relationship between the clinical performance and large deformation mechanical behavior of retrieved UHMWPE tibial inserts. Biomaterials 21 283-291. 

Kurtz S.M., J.R. Foulds, C.W. Jewett, et al. 1997. Validation of a small punch testing technique to characterize the mechanical behavior of ultra-high molecular weight polyethylene. Biomaterials 18 1659-1663. 

Pistner, H., Stallforth, H., Gutwald, R., Muhng, J., Reuther, J., Michel, C., 1994. Polyfr-lactide) a long-term degradation study in vivo, II. Physico-mechanical behavior of implants. Biomaterials 15, 439—450. 

Matsumoto, H., Takamatsu, T., Fiikada, E., Kimura, T., and Saigusa, M. The mechanical behaviors on nonthrombogenic-ity. The full manuscript of the 1975 symposium on biomaterials, Kyoto University, Kyoto, August 29-30,1975. 

To mimic the mechanical behavior of the native tissue is a basic assumption to facilitate the biointegration and function of the substitute. Incorporation of fibers to the biomaterial matrix opens the way to inhomogeneity, anisotropy, nonlinearity, and viscoelasticity features. Provided that interfacial binding between matrix and fibers in the composite goes on, mechanical properties could be tailored by varying the amount and orientation of fibers embedded, to suit the purpose applications, whether it s related to hard or soft tissue substimtes. Individual fibers, no matter how small and isolated compared to fibrous structure, could affect mechanical properties. To be effective, fibers principal direction should be considered and controlled. 

Nagapudi K, Brinkman WT, Thomas BS, Park JO, Srinivasarao M, Wright E, Conticello VP, Chaikof EL (2005) Viscoelastic and mechanical behavior of recombinant protein elastomers. Biomaterials 26 4695-4706... 

Rarely one material provides all the requirements for a given biomedical application and, in regard to biomaterial/scaffold for tissue engineering of bone and cartilage, this statement is even more accurate. Nevertheless, a set of requirements must be fulfilled, namely adequate mechanical behavior, suitable morphology, and sttuctural/functional properties (Marimuthu and Kim, 2009). 

J. S. Bergstrom, C. M. Rimnac, and S. M. Kurtz. Prediction of multiaxial mechanical behavior for conventional and highly crosslinked UHMWPE using a hybrid constitutive model. Biomaterials 24 (8), 1365-1380 (2003). 

Based on their behavior in living tissue, polymeric biomaterials can be divided into two groups biostable and biodegradable. Biostable polymers are used when permanent aids are needed, e.g., as prostheses [13]. Biostable polymers, typically polyethylene and poly(methyl methacrylate), should be physiologically inert in tissue conditions and maintain their mechanical properties for decades [11]. 

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