Mebendazole contraindications

Mebendazole is contraindicated in patients witii known hypersensitivity. Mebendazole is also contraindicated during pregnancy (Category C). The drug, like albendazole, has exhibited embryotoxic and teratogenic effects in experimental animals. Administration of mebendazole with tiie hydantoins and carbamazepine may reduce plasma levels of mebendazole. 

Mebendazole is teratogenic in animals and therefore contraindicated in pregnancy. It should be used with caution in children younger than 2 years of age because of limited experience and rare reports of convulsions in this age group. Plasma levels may be decreased by concomitant use of carbamazepine or phenytoin and increased by cimetidine. Mebendazole should be used with caution in patients with cirrhosis. 

Toxicity Mebendazole toxicity is limited to gastrointestinal irritation. However, the drag is contraindicated in pregnancy because of possible embryotoxicity. 

Mebendazole is widely used for the treatment of nematode infections but is contraindicated in the pregnant patient because of possible embryotoxicity. Think back over the dmgs used for the treatment of bacterial, fungal, protozotd, and viral infections. 

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