MC as a Wound Healing System

allow for easy and painless release from the wound. 

The never-dried microbial cellulose prepared showed unique physical, chemical, and mechanical properties. The microbial cellulose displays high crystallinity 60%, a high water holding capacity up to 200 times its dry mass, a well-developed surface area comprised of nanofibers and tensile strength of 92 Mpa. The materials were very comfortable, conformable and are transparent. The transparency of the never-dried 

A number of questions concerning this material remain yet xmsolved. First, there is no clear indication on its mechanisms of action in the woxmd healing process, which is most likely to be a result of its xmique nanostructure, hydrophilicity and porosity 

Microbial cellulose is found to be an optimal material for skin tissue repair due to its ability to provide a moist environment for wound healing and pain free dress changing. Unfortrmately, microbial cellulose itself has no antimicrobial activity to prevent wound infection. However the lack of antimicrobial activity of microbial cellulose is the main issue to be tackled. To improve the antimicrobial activity of microbial cellulose, researchers have introduced different materials such as benzalkonium chloride, chitosan and metallic nanoparticles into microbial cellulose. Among them metallic nanoparticles such as copper, silver [56] and ZnO [57] have been recently reported as excellent antimicrobial agents. Due to the electron-rich oxygen atoms in the microbial cellulose macromolecules and the large surface area of nanoporous microbial cellulose effective as nanoreactor, the in-situ metallization technique was successfully applied to the synthesis of Ag and microbial cellulose nanocomposite, which could in turn serve as antimicrobial skin tissue repair material. 

A composite of microbial cellulose and Ag obtained by an ion exchange of sodium to silver salt was performed in an AgNO solution, followed by thermal reduction. By using oxidized microbial cellulose nanofibers as a reaction template, strong ion 

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