Mass spectrometry of derivatives

Friedel-Crafts and Grignard processes applied to, 6, 251-289 gas-liquid chromatography of derivatives of, 19, 95-147 gel chromatography of, 25, 13-51 halogen oxidation of simple, 3,129-184 halogenated, 22, 177-227 infrared spectra of, 12, 13-33 infrared spectroscopy of, 19, 23-49 mass spectrometry of derivatives of,... 

Purdon JG, Pagotto JG, Miller RK. 1989. Preparation, stability, and quantitative analysis by gas chromatography and gas chromatography-electron impact mass spectrometry of tert-butyldimethylsilyl derivatives of some alkylphosphonic and alkyl methylphosphonic acids. J Chromatogr 475 261-272. 

Different strains of E. coli have unique fingerprints when analyzed by MALDI mass spectrometry of whole cells, as illustrated by the spectra of Figure 9.3. Many peaks appear at the same masses in all of the spectra, with only modest intensity variations. A few peaks also vary dramatically in intensity for these four strains. We expect the spectra to be similar, since all the strains are laboratory derivatives of the single E. coli strain, K-12. Genetic modifications can, and most likely do, affect biological functions such as tran-... 

R. C. Beavis and B. T. Chait. Cinnamic Acid Derivatives as Matrices for Ultraviolet Laser Desorption Mass Spectrometry of Proteins. Rapid Commun. Mass Spectrom., 3(1989) 432-435. 

The reaction was second order in acid and first order in substrate, so both rearrangements and the disproportionation reaction proceed via the doubly-protonated hydrazobenzene intermediate formed in a rapid pre-equilibrium step. The nitrogen and carbon-13 kinetic isotope effects were measured to learn whether the slow step of each reaction was concerted or stepwise. The nitrogen and carbon-13 kinetic isotope effects were measured using whole-molecule isotope ratio mass spectrometry of the trifluoroacetyl derivatives of the amine products and by isotope ratio mass spectrometry on the nitrogen and carbon dioxide gases produced from the products. The carbon-12/carbon-14 isotope... 

The intermediacy of the radical cations of isotoluenes (methylenecyclohexadienes) and their derivatives is a common feature in organic mass spectrometry however, it is widely ignored because of the rather difficult experimental access to neutral isotoluenes. Again, the reader is referred to the discussion on methylenecyclohexadienes in the 1990 review on ionized alkylbenzenes7. An early paper by Lifshitz and Bauer150 on mass spectrometry of bicyclo[3.2.0]hepta-2,6-diene, another C7H8 isomer, as well as of bicyclo[3.2.0]hept-6-ene and one of its isomers, cyclohepta-1,3-diene, may also be mentioned in this context. 

Scribe, P. Guezennec, J. Dagaut, J. Pepe, C. Saliot, A. Identification of the Position and the Stereochemistry of the Double Bond in Monounsaturated Fatty Acid Methyl Esters by Gas Chromatography/Mass Spectrometry of Dimethyl Disulfide Derivatives. Anal. Chem. 1988, 60, 928-931. 

Pepe, C. Sayer, H. Dagaut, J. Couffig-nal, R. Determination of Double Bond Positions in Triunsaturated Compounds by Means of Gas Chromatography/Mass Spectrometry of Dimethyl Disulfide Derivatives. Rapid Commun. Mass Spectrom. 1997, 77,919-921. 

Indole derivatives are widespread natural compounds, and mass spectrometry of indole derivates, [225,226] especially of indole alkaloids, has been a topic of interest ever since. [227-229]... 

Rodriguez, J.G. Urrutia, A. Canoira, L. Electron Impact Mass Spectrometry of Indole Derivatives. Int. J. Mass Spectrom. Ion Proc. 1996, 752,97-110. 

Figure 2. Symmetrical splitting (mass spectrometry) of the tetra-TMSi derivative of 4,4 -dihydroxytruxillic acid.

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