Manufacturing processes aluminum foil sealing

Many tablet medications intended for unit dose applications are protected by the familiar blister packs, an example of which is shown in Figure 10-26. These are typically manufactured with laminated materials that consist of a transparent polymer, an aluminum foil, and an interfacial adhesive. There are many variations of this construction. The transparent polymer layer is first dimpled with a heated die to produce the tablet cavities. The web material, consisting of the aluminum foil and adhesive, is thermally bonded under pressure to the perimeter of the cavities after the tablet is inserted. This is a continuous process in which the line speed, compression force, and temperature must be controlled to assure a hermetically sealed package. 

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