Mammals bioconcentration factors

There have been a nnmber of estimates of bioconcentration factors for total PCBs in aqnatic species following long-term exposure to PCB mixtures (EHC 140). Values for both invertebrates and hsh have been extremely variable, ranging from values below 1 to many thonsands. Bioaccnmnlation factors for birds and mammals for different Aroclors have indicated only limited degrees of bioaccumulation from food, for example, 6.6 and 14.8 for the whole carcasses of big brown bats Eptesicus fuscus) and white pelican (Pelecanus erythrorhynchos), respectively (see Environmental Health Criteria 140). 

Toxicity It is carcinogenic, hepatotoxic, nephrotoxic, and mutagenic to mammals Chronic toxicity may be predominant for DEHP no obvious acute toxicity Bioconcentration factor (BCF) is high, and the persistence is medium... 

Bioaccumulation is generally referred to as a process in which the chemical concentration in an organism achieves a level that exceeds that in the respiratory medium (e.g., water for a fish or air for a mammal), the diet, or both. The extent to which chemicals bioaccumulate is expressed by several quantities, including the bioconcentration factor (BCF), bioaccumulation factor (BAF), biomagnification factor (BMF), and trophic or food web magnification factor (TMF) [6]. The ecological, biological and chemical parameters involved in the transfer and accumulation of contaminants in food webs are complex. 

Like fish and mammals, vegetation can absorb organic contaminants. In the case of vegetation, the bioconcentration factor can be expressed relative to the mass of compound per unit mass of soil. The exact expression for vegetation is... 

The evaluation of the results from the environmental fate leads to a predicted environmental concentration (PEC) of the pesticide representing the exposure level. The accumulation in the food chain of fish is expressed as BAF ( bioaccumulation factor in aquatic environment), that of mammals and birds as BCF (bioconcentration factor in terrestrial environment). Accumulation increases the exposure. The NOAEL (no observed adverse effect level) represents the hazard level. It is the result... 

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