Malabsorption hypomagnesemia

Prolonged nasogastric suction Malabsorption syndromes Extensive bowel resection Acute and chronic diarrhea Intestinal and biliary fistulas Protein-calorie malnutrition Acute hemorrhagic pancreatitis Primary hypomagnesemia (neonatal)... 

Hypomagnesemia is usually associated with disorders of the intestinal tract or kidney. Drugs or conditions that interfere with intestinal absorption or increase renal excretion of magnesium can result in hypomagnesemia (Table 50-6). Decreased intestinal absorption as a result of small bowel disease is the most common cause of hypomagnesemia worldwide. These disorders include regional enteritis radiation enteritis ulcerative colitis acute and chronic diarrhea pancreatic insufficiency and other malabsorptive syndromes small-bowel bypass surgery and chronic laxative abuse. ... 

Hypomagnesemia Diarrhea, malabsorption, anabolism magnesium-wasting drug therapy Increase magnesium intake... 

E. Hypomagnesemia can be associated with a number of acute or chronic disease processes (malabsorption, pancreatitis, DKA). It may result from chronic diuretic use or alcoholism. It is a potentially serious, life-threatening consequence of hydrofluoric acid poisoning. 

Hypomagnesemia is caused by reduced oral or intestinal intake (magnesium-poor diet, malabsorption, alcohol abuse), increased gastrointestinal or renal excretion, hormonal effects (sexual and thyroid hormones, parathormone), and water and electrolyte imbalance. 

Complex relations exist between Mg and carbohydrate metabohsm. Diabetes is frequently associated with Mg deficit and insulin may play an important role in the regulation of intracellular Mg content by stimulating cellular Mg uptake. Hypomagnesemia is the most common ionic abnormality in alcoholism because of poor nutritional status and Mg malabsorption, alcoholic ketoacidosis, hypophosphatemia, and hyperaldosteronism secondary to liver disease. 

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