Magnetic latex particles

FIGURE 12.30 The effect of pH on the desorption of preadsorbed nucleic acid molecules onto cationic thermally sensitive magnetic latex particles. Adsorption was performed using 10 mW phosphate buffer, pH 5.2, 10 M NaCl at 20°C, with an incubation time of 180 min. (From Elaissari, A. et al., J. Magn. Magn. Mater., 2001. With permission.)... 

The admlceUar polymerization concept was also applied to the synthesis of thermosensitive magnetic latex particles based on V-isopropylacrylamide (NIPAM). In this case, however, the polymerization could be better defined as seeded precipitation polymerization owing to the water solubility of this monomer. Kondo et al. [116] were among the first to synthesize PNIPAM particles using Fe304 nanoparticles covered with two layers of OA and SDBS. V,V -Methylene bisacrylamide... 

Still using the same two-step procedure, monodisperse and thermoresponsive magnetic latex particles based on PNIPAM were prepared [157, 158], Anionic iron oxide nanoparticles were first adsorbed onto preformed cationic particles of various compositions [PS, poly(styrene-co-NIPAM) core-shell, or PNIPAM], The obtained heterocoagulates were then encapsulated with crosslinked PNIPAM through seeded precipitation polymaization (Fig. 24). The magnetic content varied from 6 to 23 wt%. These particles were successfiiUy used for the covalent immobilization of antibodies, and the resulting conjugates were tested as solid phases in immunoassays [159]. 

The adsorption and the chemical grafting of an antibody (anti-Alpha-foeto protein) onto thermosensitive magnetic latex particles is investigated as a function of pH ionic strength and temperature. The hydrophilic magnetic latexes bearing surface carboxylated groups are prepared... 

T. Su2aita, Preparation of magnetic latex particles by emulsion polymerization of styrene in the presence of a ferrof luid, J. Appl. Polym. Sci. 1993, 50, 765-776 ... 

T. Suzaita, Preparation and characterization by thermal analysis of magnetic latex particles,/. Appl. Potym. Sci. 1993, 48, 1539 1547. 

Magnetic Latex Particles via Polymerization in Dispersed Media. 319... 

Magnetic Latex Particles from Preformed Polymers. 321... 

Indeed, works on the magnetic latex particles preparation via miniemulsion polymerization have shown many limitations to this method such as (1) an inhomogeneous distribution of the magnetic... 

Transmission microscopy analysis of magnetic latex particles. (From Montagne, F. et al. 2006. J. Polym. Sci. Part A Polym. Chem. 44 2642-2656. With permission.)... 

FIGURE 14.6 Modification of magnetic latex particles via an emulsification and evaporation process. 

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