Magnesium hydroxide induced

A variety of adverse effects have been reported following the use of antacids. If sodium bicarbonate is absorbed, it can cause systemic alkalization and sodium overload. Calcium carbonate may induce hypercalcemia and a rebound increase in gastric secretion secondary to the elevation in circulating calcium levels. Magnesium hydroxide may produce osmotic diarrhea, and the excessive absorption of Mg++ in patients with renal failure may result in central nervous system toxicity. Aluminum hydroxide is associated with constipation serum phosphate levels also may become depressed because of phosphate binding within the gut. The use of antacids in general may interfere with the absorption of a number of antibiotics and other medications. 

Plate-like particles of interest in this context include mica, aluminum flake, hammered glass, magnesium hydroxide and talc. Physical properties of composites containing these additives depend strongly on the flow-induced morphology and on the distribution of residual stresses [31]. 

A study in 12 healthy subjects found that pretreatment with alumini-um/magnesium hydroxide (Maalox) 30 mL (10, 2 and 0.5 hours before dofetilide) did not affeet the pharmacokinetics of a single 500-microgram dose of dofetilide, nor the dofetilide-induced change in QTc interval. No speeial preeautions appear to be necessary. 

Didanosine is extremely acid labile at pH values below 3, so one ofthe formulations contains buffering agents (dihydroxyaluminium sodium carbonate and magnesium hydroxide) to keep the pH as high as possible to minimise the acid-induced hydrolysis. Ciprofloxacin forms insoluble non-absorbable chelates with these metallic ions in the buffer so that its bioavailability is markedly reduced. See also Quinolones + Antacids or Calcium compounds , p.328. 

So, the aggregation of xanthan molecules was induced by the presence of both cations and proteins. Furthermore, the aggregation of xanthan C chains was probably enhanced by the particular nature of the fermentation conditions in addition to the interactions with calcium or magnesium hydroxide ions and added proteins. These peculiar conditions of culture seem to be indirectly involved in the mechanism of aggregation by the cells themselves and possibly by the chain length of the xanthan synthesized. 

Flush with large amounts of water, sodium bicaibortate paste to neutralize acid on tfte skin, magnesium hydroxide, water, egg whites, or soap solution (instead of inducing emesis)... 

Gastric lavage and emetics should be avoided after exposure to phosphoric or other acids, should not be induced. An exposed area should be washed with copious amounts of water and a neutralizer such as magnesium oxide, lime water, or aluminum hydroxide gel. Eyes should be irrigated with large amounts of water. 

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