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Macrophage targeted clinical responses

IV. FIRST DEMONSTRATION OF CLINICAL RESPONSES TO MACROPHAGE-TARGETED GLUCOCEREBROSIDASE... [Pg.265]

It has been reported to stimulate humoral and cellular immune responses in combination with several subunit antigens. It has also been proven safe, and does not cause any major adverse reactions. In clinical trials it has already been used with influenza, HSV or HIV antigens, and has been marketed as part of an enhanced influenza vaccine for the elderly. MF59 does not form a depot at the injection site, but targets macrophages and dendritic cells at the site of injection and in lymph nodes. [Pg.1425]

There are some studies where the ability of berberine to inhibit the HIV-I has been evaluated [107,119].Zhaet al. identified a key cellular mechanism underlying the protective effect of berberine on HIV Pl-induced inflammatoiy response in macrophages. Modulation of the endoplasmic reticulum (ER) stress response represents a potential therapeutic target for various inflammatory diseases and metabolic syndromes, including HIV Pl-associated atherosclerosis. However, in vivo and clinical studies are needed to further clarify the putative application of berberine in anti-HIV therapy. [Pg.4483]

See other pages where Macrophage targeted clinical responses is mentioned: [Pg.542]    [Pg.268]    [Pg.272]    [Pg.277]    [Pg.277]    [Pg.250]    [Pg.250]    [Pg.268]    [Pg.268]    [Pg.271]    [Pg.272]    [Pg.277]    [Pg.293]    [Pg.242]    [Pg.163]    [Pg.145]    [Pg.227]    [Pg.288]    [Pg.94]    [Pg.203]    [Pg.149]    [Pg.236]    [Pg.266]    [Pg.182]    [Pg.58]    [Pg.162]    [Pg.1270]    [Pg.126]    [Pg.324]    [Pg.85]    [Pg.578]    [Pg.155]    [Pg.249]   
See also in sourсe #XX -- [ Pg.268 ]

See also in sourсe #XX -- [ Pg.268 ]



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Macrophage targeted

Response, target

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