Macrocyclic polyamines and their metal complexes

MACROCYCLIC POLYAMINES AND THEIR METAL COMPLEXES A NOVEL TYPE OF ANTI-HIV AGENT... 

The present volume is the fourth in the series and covers the topics lithium in biology, the structure and function of ceruloplasmin, rhenium complexes in nuclear medicine, the anti-HIV activity of macrocyclic polyamines and their metal complexes, platinum anticancer dmgs, and functional model complexes for dinuclear phosphoesterase enzymes. The production of this volume has been overshadowed by a very sad event—the passing away of the senior editor, Professor Robert W. Hay. It was he who conceived the idea of producing this series and who more than anyone else has been responsible for its continuation. A tribute by one of his many friends, Dr. David Richens, is included in this Volume. 

Macrocyclic polyamines and their metal complexes 86PAC1461, 86PAC1511. 

Complexes of other metals are used to sensitize emulsions, and some are used to sensitize even further (supersensitize) gold-sensitized emulsions. " Among these are (NH4)2[PtCl4], (NH4)2[PdCl4], (NH4)2[PdCy, K2[IrCl6] and similar compounds with ruthenium and the other halides. Sensitization by iridium salts and complex ions has been reviewed recently. Mechanisms of action of palladium(II) salts and complex ions on gold-sensitized emulsions have been studied. Several phosphine complexes of palladium and platinum, for example (2), are reported to be effective sensitizers, as are many macrocyclic polyamine compounds and their metal complexes,for example the Cu", Ni", Fe " and Rh " chelates of the cyclen ligand, 1,4,7,10-tetraazacyclododecane (3). 

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