MacLeod drugs

Nikolai LN, McClure EL, MacLeod SL, Wong CS (2006) Stereoisomer quantification of the Beta-blocker drugs atenolol, metoprolol, and propranolol in wastewaters by chiral high-performance liquid chromatography-tandem mass spectrometry. J Chromatogr A 1131 103-109... 

J. Aranda, S. MacLeod, K. Renton, and N. Eade, Hepatic microsomal drug oxidation and electron transport in newborn infants, J. Pediatr, 85, 534 (1974). 

Macleod et al. [92] have studied the potential of pectin-chitosan-hydroxypropyl methylcellulose films for colonic drug delivery [92]. The results showed that in all cases the tablets were able to pass through the stomach and small intestine intact. The tablets started to break up once they were in the colon, due to degradation of the coat by colonic bacteria. 

Macleod, G.S., Fell, J.T., Collett, J.H., Sharma, H.L., and Smith, A.M., Selective drug delivery to the colon using pectin chitosan hydroxypropyl methylcellulose film-coated tablets, Int J. Pharm., 187 251-257 (1999). 

Radde IC (1985) Mechanisms of drug absorption and their development. In Macleod SM Radde IC eds. Textbook of pediatric clinical pharmacology. Littleton, MA, PSG Publishing Company, pp 17-43. 

Macleod, G. S., Fell, J. T., and Collett, J. H. (1999), An in vitro investigation into the potential for bimodal drug release from pectin/chitosan/HPMC-coated tablets, Int. I. Pharm., 188,11-18. 

Aortic arch atheroma is now increasingly diagnosed by transesophageal echocardiography in patients with TIAs or ischemic stroke, but so far there are no surgical, or indeed medical, treatment options over and above controlling vascular risk factors and antiplatelet drugs. One trial of medical treatment has been started, the Aortic Arch Related Cerebral Hazard (ARCH) trial (MacLeod et al. 2004). 

Macleod, A.D. Tolentino, L. Tozer, T.N. Glucocorticoid-dextran conjugates as potential prodrugs for colon-specific delivery steady-state pharmacokinetics in the rat. Biopharm. Drug Disp. 1994,15, 151-161. 

Rajchgot, P. Radde, I.C. MacLeod, S.M. Influence of specific gravity on intravenous drug delivery. J. Pediatr. 1981, 99, 658-661. 

Rieder MJ, Matsui DM, MacLeod S (2003) Myths and challenges—drug utilization for Canadian children. Paediatr Child Health 8(Suppl A) 7... 

Baker R, MacLeod AM. In Kozikowski AP, eds. Drug Design for Neuroscience, New York Raven, 1993 61-85. 

Sodiiun bromide was shown by MacLeod to relieve drug addiction, chloral, and cocaine addiction, also alcoholism. It relieves certain nervous disorders. 

MacLeod, J.N. B.H. Shapiro. 1989. Growth hormone regulation of hepatic drug-metabolizing enzymes in the mouse. Biochem. Pharmacol. 38 1673-7. 

Macleod G. S., Fell J. T, Collett J. H. (1997). Studies on the physical properties of mixed pectin/ethylcellulose films intended for colonic drug delivery. 157,53-60. 

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