Lung lavage fluid

Berghem L, Hansson M, Lundborg M, et al. 1987. Fibronectin concentrations in lung lavage fluid after inhalation exposure to low levels of metals. Environ Res 43 79-85. 

Suzuki Y. 1988. Reduction of hexavalent chromium by ascorbic acid in rat lung lavage fluid. Arch Toxicol 62 116-122. 

Haslam, P.L., Cromwell, O., Dewar, A. and Turner-Warwick, M. (1981a). Evidence of increased histamine levels in lung lavage fluids from patients with cryptogenic fibrosing alveolitis. Clin. Exp. Immunol. 44, 587-593. 

Mitra R, et al. Enhanced pulmonary delivery of insulin by lung lavage fluid and phospholipids. Int J Pharm 217(1 —2) 25—31, 2001. 

Leukotrienes may also play a pathogenic role in hypoxic pulmonary hypertension. Itypoxic pulmonary vasoconstriction in sheep is prevented or reversed by FPL-55712. LTC. and LTD. are present in lung lavage fluid obtained from human nevrtxDrns with a clinical diagnosis of persistent pulmonary hypertension and hypoxemia. ... 

Recently, Stenmark et al measured eicosanoids and PAF in the lung lavage fluid from neonatal calves exposed to two weeks of high-altitude hypoxia. Prostacyclin, thromboxane and PAF were increased and accompanied by... 

Gasser, H., Strohmaier, W., Schlag, G. et al. (1991) Characterization of phosphatidylcholines in rabbit lung lavage fluid by positive and negative ion fast-atom bombardment mass spectrometry. J. Chromatogr. Biomed. Applic., 562, 257-66. 

Sample preparation Centrifuge lung lavage fluid at 4° at 450 g for 10 min. Shake 10 mL supernatant and 40 mL chloroform MeOH 2 1 at 4° for 3 min (Caution Chloroform is a carcinogen ). Remove the lower organic phase and wash it with 2 mL 50 mM NaCl, centrifuge, dry under a stream of nitrogen at 45°, reconstitute with 500 ixL mobile phase, vortex at 4° for 1 min, inject a 100 itL aliquot. 

Previous research has suggested that VA deficiency is associated with a reduction in the production of IgA such a decrease may be related to the often-increased severity of infections observed in VA-deficient children and the poor recovery of mucosal epithelia following infection in animal models (see chapter in this book by R. Semba). The IgA response to influenza A in VA-deficient mice was reduced in lung tissue, yet influenza A-specific IgG titers in tracheal and lung lavage fluids did not differ between VA-deficient and control mice [25]. 

Beek BD, Gerson B, Feldman HA, Brain JD. Lactate dehydrogenase isoenzymes in hamster lung lavage fluid after lung injury. Toxicol Appl Pharmacol 1983 71 59-71. 

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