Lung, chemokine sources

Table 1 Sources of Chemokines from Resident Lung Cell Populations...

Cook EB, JL Stahl, CM Lilly, KJ Haley, H Sanchez, AD Luster, EM Graziano, ME Rothenberg. 1998. Epithelial cells are a major cellular source of the chemokine eotaxin in the guinea pig lung. Allergy Asthma Proc 19 15. 

Last but not least, the eosinophil is another important participant in the pathogenesis of asthmatic inflammation and about 80% of the asthma patients show an increased number of eosinophils. Airway epithelial cells are an important source of chemokines and contribute to recruitment of eosinophils to and within the lung. Predominantly, the CCR3 ligand CCLll (eotaxin) attracts and activates eosinophils by acting via the most prominent chemokine receptor on eosinophils CCR3. 

Sources of Chemokines in Human Lung Cells or Cell Lines Studied in Vitro... 

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