Lung cancer incidence

Age adjusted lung cancer incidence in the period 1966-1985 was correlated against smoking habits (expressed as average number of cigarettes smoked per day in the grown population) for men and women. 

Albanes D, Heinonen OP, Taylor PR, Virtamo J, Edwards BK, Rautalahti M, Hartman AM, Palmgren J, Freedman LS, Haapakoski, J, Barrett MJ, Pietinen P, Malila N, Tala E, Liippo K, Salomaa ER, Tangrea JA, Teppo L, Askin FB, Taskinen E, Erozan Y, Greenwald P and Huttunen JK. 1996. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study effects of base-line characteristics and study compliance. J Natl Cancer Inst 88 1560-1570. 

Steenland K, Ward E Lung cancer incidence among patients with beryllium disease a cohort mortality study. J Natl Cancer Inst 83 1380-1385, 1991... 

Rafnsson V, Gunnarsdottir H Lung cancer incidence among an Icelandic cohort exposed to diatomaceous earth and cristobalite. Stand J Work Environ Health 23(3) 187-92, 1997... 

NCSDC Case-cohort11 6.3 2464 M Protective effect on lung cancer incidence was found for folate and vitamin C, particularly, for current smokers carotenoids do not show an evident protective activity 148... 

Reid ME, Duffield-Lillico AJ, Garland L, etal. Selenium supplementation and lung cancer incidence an update of the Nutritional Prevention Cancer Trial. Cancer Epidemiol Biomark Prev 2002 11 1285-1291. 

Sprague-Dawley rats were exposed to radon progeny up to 82 days. The lung cancer incidence in rats was... 

Interest in vitamin A and its synthetic analogs as a potential factor in the prevention and treatment of certain types of cancer has been growing. In addition, there is evidence that vitamin A may be related to pollutant toxicity. Recent epidemiological studies in humans with a sample of 8000 men in Chicago showed a low lung cancer incidence in those with a high vitamin A level in the diet, while the incidence was higher in those people with a low dietary vitamin A. Experimental studies show that rats exposed to PCB, DDT, and dieldrin caused a 50% reduction in liver vitamin A store. In another study, rats deficient in retinol were shown to have a lowered liver cytochrome P-450 activity. The effect of vitamin A deficiency on MFO enzymes, however, depends on several factors such as substrate, tissue, and animal species. 

Smoking and exposure to radon have a synergistic multiplicative effect on lung cancer incidence. I126 This effect has been observed in instances of household radon/smoking combinations 127 as well as jn industrial dual exposures, most notably in mining populations. 128 No well-understood mechanism exists at this time to account for this effect. 

Wakalee HA, Chang ET, Gomez SL, et al. Lung cancer incidence in never smokers. J Clin Oncol2007 25(5) 472 8. 

Grimsrud TK, Berge SR, Martinsen JI, Andersen A. Lung cancer incidence among Norwegian nickel-refinery workers 1953-2000. J Environ Monit 2003 5 190-7. 

Islam SS, Schottenfeld D. DecUning FEVi and chronic productive cough in cigarette smokers A 25-year prospective study of lung cancer incidence in Tecumseh, Michigan. Cancer Epidemiol Biomarkers Prev 1994 3 289-298. 

Strauss GM. The Mayo Lung Cohort A regression analysis focusing on lung cancer incidence and mortality. J Clin Oncol 2002 20 1973-1983. 

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