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4- Loperamide hydrochloride

Figure 4.8 shows the comparison of three lots of loperamide hydrochloride, each obtained from a different supplier. The displayed thermograms represent normal behavior for this material, and while the figure shows the uniqueness of each source, the variations were within acceptable limits. Owing to the decomposition that followed on the end of the melting endotherm, specific heats of fusion were not calculated in this case. [Pg.86]

Fig. 4.8. DSC thermograms of three lots of loperamide hydrochloride obtained from different suppliers. Fig. 4.8. DSC thermograms of three lots of loperamide hydrochloride obtained from different suppliers.
Loperamide Hydrochloride and Simethicone Imodium Advanced 2/125 mg chewable tablets... [Pg.100]

Fixed dose combination of loperamide hydrochloride with furazolidone. [Pg.475]

Killinger, J.M., Weintraub, H.S., Fuller, B.L. Human pharmacokinetics and comparative bioavailability of loperamide hydrochloride, J. Clin. Pharmacol. 1979, 19, 211-218. [Pg.238]

R. T. Sane, R. S. Samant, and V. G. Nayak, High-performance liquid chromatographic determination of loperamide hydrochloride and dilazep dihydrochloride in pharmaceuticals, Indian Drugs, 24 150(1986). [Pg.435]

Q6 To which category of drugs does loperamide hydrochloride belong and what is its mechanism of action ... [Pg.85]

Q6 Loperamide hydrochloride is an opioid. The starting dose will be 4 mg, which can be reduced to 2 mg, three times a day for five days if necessary. Opioids act on // opiate receptors in the myenteric plexus of the intestine and may modulate acetylcholine release to reduce peristalsis. They trigger mucosal transport of ions and water out of the lumen and cause a reduction in secretion. The absorption of fluid and electrolytes is increased since the stool remains in the colon for a longer period. Loperamide does not produce sedation or other central effects associated with opiates, since it does not cross the blood-brain barrier. [Pg.267]

Infra-red Spectrum. Principal peaks at wavenumbers 1600, 700, 830, 765, 964, 986 (loperamide hydrochloride, KBr disk). [Pg.710]

Following oral administration of capsules containing 8 mg of loperamide hydrochloride to 6 subjects, peak serum concentrations of about 0.002 pg/ ml were attained in about 4 to 5 hours (J. M. Killinger et ai, J. din. Pharmac., 1979,19, 211-218). [Pg.710]

Levomethadyl Acetate Hydro- Loperamide Hydrochloride Bromhexine Hydrochloride... [Pg.1091]

See other pages where 4- Loperamide hydrochloride is mentioned: [Pg.884]    [Pg.1418]    [Pg.473]    [Pg.710]    [Pg.607]    [Pg.59]    [Pg.2070]    [Pg.2070]    [Pg.2071]    [Pg.418]    [Pg.85]    [Pg.389]    [Pg.709]    [Pg.710]    [Pg.1083]   
See also in sourсe #XX -- [ Pg.19 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]

See also in sourсe #XX -- [ Pg.710 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]

See also in sourсe #XX -- [ Pg.19 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]

See also in sourсe #XX -- [ Pg.709 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]

See also in sourсe #XX -- [ Pg.395 ]

See also in sourсe #XX -- [ Pg.19 , Pg.341 ]



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