Lithographic pencil

Several multiple cell SECM studies have focused on the preferential patterning of cells on a transparent solid support prior to SECM studies. The coUagen-gel-imbedded ceU matrix discussed at length in other sections has been applied to multiple human ceU studies. The use of poly(dimethylsiloxane) soft lithographic processes has also been used because they easily facilitate the acquisition of statistically valid SECM measurements and local delivery of a variety of solutes to the cells. " Finally, the use of the microelectrode as a lithographic pencil capable of writing patterns preferentially adhering one cell over another has also been reported. 

Step 1. The artist draws or paints on a flat polished stone (typically limestone) with a greasy substance such as a lithographic crayon (a soft waxy/greasy crayon), paint, or pencil. The stone absorbs this greasy substance and retains it. 

The artist uses crayons, pencils and touche, a liquid suspension of naturally occurring fats, soaps and oils to which pigments are added. The differential interactions of these artistic materials with the stone need to be appreciated by the lithographer so that s(he) can instruct the artists so that they can achieve their desired effect. 

Major AppUcations Display device, optical sensors, - thin-flhn device, incandescent electric lamps,9 photoreceptors,io lithographic process," inks," pencil leads," paints," adhesives," plastic materials," molding materials," steel plates," detection of albumin," treatment of amyloidosis disorders,2o treatment of apolipoprotein E-related diseases i Safety/Toxicity Eye irritation tesF ... 

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