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Lipoproteins abnormal

One of the most striking lipoprotein abnormalities of familial LCAT deficiency is the presence in the LDL fraction of abnormally large particles, containing variable but unusually great proportions of unesteri-fied cholesterol and lecithin (F6, G14, N5). Recently, an abnormal LDL lipoprotein, identical to cholestatic lipoprotein, LP-X (see Section 8.1) was demonstrated in plasma from patients with familial LCAT deficiency (Ml, T2). Identity of the abnormal LDL lipoprotein and LP-X was shown by electron microscopy, composition, and immunological techniques (T2). The amount of LP-X in plasma of patients with obstructive jaundice ranged from 40 to 1200 mg/100 ml (M3) whereas plasma from patients with familial LCAT deficiency contained 49 to 152 mg/100 ml (T2). [Pg.139]

Before primary disorders can be diagnosed, secondary causes of the phenotype must be considered. The more common conditions are summarized in Table 35-3. The lipoprotein abnormality usually resolves if the underlying disorder can be treated successfully. [Pg.784]

Breckenridge WC, Little JA, Alaupovic P, Wang CS, Kuksis A, Kakis G, Lindgren F, Gardiner G (1982) Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase. Atherosclerosis 45 161-179... [Pg.544]

Dedecjus M, Masson D, Gautier T, de Barros JP, Gambert P, Lewinski A, Adamczewski Z, Moulin P, Lagrost L (2003) Low cholesteryl ester transfer protein (CETP) concentration but normal CETP activity in serum from patients with short-term hypothyroidism Lack of relationship to lipoprotein abnormalities. Clin Endocrinol (Oxf) 58 581-588... [Pg.544]

It has been known for some years that elevated plasma cholesterol concentrations and particular lipoprotein abnormalities are causal factors in the development of coronary heart disease, and that it is possible to lower plasma cholesterol concentrations in individuals or populations. [Pg.218]

Aly, A., Carlson, K., Johansson, C., Kirstein, P., Rdssner, S., Wallen-tin,L. Lipoprotein abnormalities in patients with early primary biliary cirrhosis. Eur. J. Clin. Invest. 1984 14 155-162... [Pg.667]

Dennison BA, Kikuchi DA, Srinivasan SR, Webber LS, Berenson GS. Parental history of cardiovascular disease as an indication for screening for lipoprotein abnormalities in children. J Pediatr 1989 115 ... [Pg.971]

Samuelsson O, Attman PO, Knight-Gibson C, et al. Effect of gemfibrozil on lipoprotein abnormalities in chronic renal insufficiency A controlled study in human chronic renal disease. Nephron 1997 75 286-294. [Pg.452]

While congenital HL deficiency is associated with increased levels of plasma total TG, the pattern of lipoprotein abnormalities is more variable and less clear-cut than that of LPL deficiency. It seems probable that other plasma and ELs can take over many of HL s functions. [Pg.544]

Phosphaddylchotine-slerol acyitransferase (EC 2.3.1.43). Plasma cholesterol and triacylglycerols increased. Lysophosphatidylcholine and cholesterol esters decreased. Turbid or milky plasma. Multiple lipoprotein abnormalities. Comeal opacities. Normochromic anemia and proteinuria, due to renal damage. Therapy by enzyme replacement. [The enzyme catalyses formation of cholesterol esters by tranter of an unsaturated fatty acid from position 2 of lecithin to the 3-OH of cholesterol]... [Pg.318]

Lipoprotein abnormalities are common in gout. The most frequent is hypertriglyceridemia, which has been reported in three-quarters of patients with primary gout (1, 2). This alteration may or may not be related to obesity, alcohol consumption, and glucose intolerance (3). Patients with gout secondary to lead nephropathy do not have hypertriglyceridemia (4). [Pg.141]

Wood, P.D.S., Stern, M.P., Silvers, A., Reaven, G.M. and Groenen, J. Prevalence of plasma lipoprotein abnormalities in a free-living population of the Central Valley, California. [Pg.64]


See other pages where Lipoproteins abnormal is mentioned: [Pg.423]    [Pg.127]    [Pg.269]    [Pg.1698]    [Pg.435]    [Pg.842]    [Pg.843]    [Pg.520]    [Pg.520]    [Pg.525]    [Pg.173]    [Pg.174]    [Pg.398]    [Pg.101]    [Pg.107]   
See also in sourсe #XX -- [ Pg.44 ]




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Lecithin:cholesterol acyltransferase lipoprotein abnormalities

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