Lipoprotein levels, classification

TABLE 72—14. Classification of Lipid and Lipoprotein Levels in Adults... 

Koch et al. determined total cholesterol, phospholipids, and fatty acids in CSF samples from 216 individuals in order to establish the lipid and apo-lipoprotein levels in Cerebrospinal Fluid (CSF) in a large group of individuals, on the basis of which a classification of CSF lipoproteins was made. The cholesterol and phospholipids are measured enzymatically by fluorometric detection of the reaction products. Earlier work had shown reduced levels of cholesterol, phospholipids, and free fatty acids in Cerebrospinal Fluid (CSF) of Alzheimer disease patients. Urine levels of F2-isoprostanes or their major metabolite were not significantly different between Alzheimer s disease patients and controls. In addition, urine and CSF F2-isoprostane levels in Alzheimer s disease patients did not correlate. These results indicate that plasma and urine F2-isoprostanes and F2-neuroprostanes do not accurately reflect central nervous system levels of these biomarkers and are not reproducibly elevated in body fluids outside of the central nervous system in Alzheimer s disease patients. 

LDL, low-density lipoproteins CHD, coronary heart disease. Classification <130 mg/dL is the desirable LI3L cholesterol level 130-159 mg/dl is borderline-high-risk >160 mg/dl is high-risk. 

Antilipemics lower lipid levels (Table 19.4). Lipids are composed of cholesterol, triglycerides, and phospholipids, which are bound to lipoproteins (Table 19.5) that transport lipids throughout the body. There are three classifications of lipoproteins ... 

TABLE 21—9. Classification of Total and Low-Density Lipoprotein Cholesterol Levels in Children and Adolescents from Families with Hypercholesterolemia or Premature Cardiovascular Disease ... 

Recently according to a new classification of HDL apoproteins, it has been observed that in coronary patients there is a decrease of Lp-A-I (lipoproteins that contain Apo-A-I, but not Apo-A-II), whereas Lp-A-I A-II (lipoproteins that contain bot apoA-I and A-II) are normal [28]. A possible predictive role for ApoA-I is supported by the paper of Ishinawa et al. [29], which shows that the levels of ApoA-I are lower in people who have lately complained of IHD. 

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