Lipids adaptation strategies

Bessa et al. (2000) proposed that the generation of trans C18 1 isomers through incomplete BH could be an adaptive strategy of rumen ecosystan to deal with stressor stimuli including rumen lipid overload. This is because some BH intermediates, such as C18 1 isomers could have a protective role to rumen bacteria in certain... 

Fig. 2 Flow cytometric differential detergent resistance (FCDR) assay strategy for the detection of DRM association of membrane proteins. A Lipid raft-associated plasma membrane proteins show high resistance to detergent treatment. B Nonraft-assocrated proteins are rapidly dissolved by even low concentrations of nonionic detergents in a short time. These processes can be followed by measnring fluorescence means before and after 5 min of detergent treatment by flow cytometry. (Adapted from Gombos et al. 2004 Wolf et al. 2006)...

Temperature and pressure extremes require different strategies. Cellular lipids, proteins and nucleic acids are sensitive to high temperatures. Hyperthermophile bacteria have ether lipids instead of the more hydrolysis sensitive ester lipids in mesophiles [13]. Enzymes from hyperthermophiles show an unusual thermostability in the laboratory, and an important aspect of protein chemistry research is to find out the stabilizing principles. Crude cell extracts of hyperthermophiles show the presence of heat inducible proteins, called chaperones, which assist in the folding of proteins during cellular synthesis. Molecular details for cold adaptation of enzymes have been reported but are less extensively studied [14]. 

Westhaus E, Messersmith PB (2001) controlled release of calcium from lipid vesicles adaption of a biological strategy for rapid gelation of polysaccharide and protein hydrogels. Biomaterials 22 453 62... 

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