Lipid antigens

NKT cells express T-cell receptors as well as receptors commonly found on NK cells. NKT cells recognize microbial lipid antigens... 

Natural killer T (NKT) cells are T cells that express T cell receptors as well as the NK1.1 receptors commonly found on NK cells. NKT cells recognize microbial lipid antigens presented by a unique class of MHC-like molecules known as CD1. They have been implicated in host defense against microbial agents, autoimmune diseases, and tumors. 

Hong S, Scherer DC, Singh N, Mendiratta SK, Serizawa I, Koezuka Y, Van Kaer L. Lipid antigen presentation in the immune system lessons learned from CDld knockout mice. Immunol Rev 1999 169 31 4. 

To investigate if LDLR is also important for lipid antigen presentation and NKT cell activation in vivo, GGC was intravenously injected into LDLR knockout (LDLR j mice or WT mice. NKT cell activation in LDLR mice was... 

Brennan, P.J., M. Heifets, and B.P. Ullom Thin-layer Chromatography of Lipid Antigens as a Means of Identifying Nontuberculous Mycobacteria. J. Clin. Microbiol. 15, 447 (1982). 

Matsumoto, Y. Kono, R. Anraku, H. Lipophilic dye for immobilized lipid antigen for immunoassay of anti-phospholipid antibody. Jpn. Kokai Tokkyo Koho JP 08105891, 1996 Chem. Abstr. 1996,125, Sim. 

Shiba, K., Y. Umezawa, T. Watanabe, S. Ogawa, and S. Fujiwara. 1980. Thin-layer potentiometric analysis of lipid antigen-antibody reaction by tetrapentylammonium (TPA+) ion loaded liposomes and TPA+ ion-selective electrode. Ana/. Chem. 52 1610-1613. 

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