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Lineage structures

It is essential for viruses to penetrate the cells of an infected host in order to subvert the cells replicative machinery towards viral replication. Clearly, it is in the interests of the host to kill such infected cells before the virus has had a chance to reproduce. Natural killer (NK) cells are cytotoxic cells that appear to have evolved to carry out just such a task. The precise lineage of NK cells is still uncertain. They are large granular lymphocytes that attach themselves to structures, presumably glycoproteins, that appear on the surface of virally infected... [Pg.177]

Taken together, these observations suggest that whatever the function of melanopsins they do not need to have a highly conserved protein structure, and in this respect differ markedly from the known photosensory opsins. Furthermore, the melanopsins do not share a conserved genomic structure with the photosensory opsins (Fig. 2), suggesting a different evolutionary lineage to the characterised photosensory opsins (Bellingham Foster 2002). [Pg.16]

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Lineage

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