Light/dark box

The sedative and anxiolytic effects of passionflower were examined in two other animal behavioral assays (staircase test, light/dark box choice test). Both anxiolytic and sedative effects occur, as well as potentiation... 

Bourin M, Hascoet M (2003) The mouse light/dark box test. Em J Pharmacol 463 55-65 Britton DR, Britton KT (1981) A sensitive open field measure of anxiolytic drug activity. 

Although there is evidence that A3AR ko mice are more prone to depressive behavior, it is also reported that they have increased performance in the elevated-plus maze and light/dark box suggestive of reduced anxiety but this is most probably a consequence of the increase in exploratory activity due to increased motor activity (Fedorova et al. 2003). 

Light-dark box Panlab, Barcelona, Spain Stoelting, Wood Dale IL, USA www.panlab. com www.anymaze. c om... 

Delta receptor knockout animals showed a strong and unexpected phenotype in assays for anxiety and depressive-like responses [53], Mutant animals explored open arms of the plus maze and visited the aversive compartment of the light-dark box significantly less than their wild-type counterparts. These indications of increased levels of anxiety, paralleled with a... 

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