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Ligand efficiency indices

Abad-Zapatero, C., Metz, J. T. Ligand efficiency indices as guideposts for drug discovery. Drug Discov. Today 2005, 10, 464 69. [Pg.460]

Abad-Zapatero, C. Ligand efficiency indices for effective drug discovery. Expert Opin. Drug Discov. 2007,2, 469 188. [Pg.278]

Ligand Efficiency Indices to Guide Fragment Hit Selection and Progression. 93... [Pg.84]

Abad-Zapatero C, Perisic O, Wass J, Bento AP, Overington J, Al-Lazikani B, Johnson ME (2010) Ligand efficiency indices for an effective mapping of chemico-biological space the concept of an atlas-like representation. Drug Discov Today 15 804-811... [Pg.110]

Abad-Zapatero C, Metz JT (2005) Ligand efficiency indices as guideposts for drag discovery. Drag Discov Today 10 464—469... [Pg.45]

Hopkins, A.L. et al. Ligand efficiency A useful metric for lead selection. Drug Discov. Today 2004, 9, 430-431. For more about its quantitation, see Abad-Zapatero, C., Metz, J.T. Ligand efficiency indices as guideposts for drug discovery. Drug Discov. Today 2005, 10, 464—469. [Pg.276]

Tanaka, D., Tsuda, Y., Shiyama, T., Nishimura, T., Chiyo, N., Tominaga, Y., Sawada, N., Mimoto, T., and Kusunose, N. (2011) A practical use of ligand efficiency indices out of the fragment-based approach ligand efficiency-guided lead identification of soluble epoxide hydrolase inhibitors. Journal of Medicinal Chemistry, 54, 851-857. [Pg.511]

See other pages where Ligand efficiency indices is mentioned: [Pg.8]    [Pg.271]    [Pg.251]    [Pg.251]    [Pg.105]    [Pg.201]    [Pg.203]    [Pg.204]    [Pg.251]    [Pg.251]    [Pg.459]    [Pg.462]   
See also in sourсe #XX -- [ Pg.93 , Pg.203 ]



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Ligand indexing

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