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Libraries screening rapidly

Recent years has seen a paradigm shift in the way drugs are discovered and produced. Many areas of drug discovery rely on combinatorial approaches to produce more opportunities and screen more compounds. This has altered the way analysis is performed in all areas and none more so than in the analysis of combinatorial libraries. The rapid development of specialised coupled chromatography-mass spectrometry techniques for... [Pg.172]

C.A. Mueller, W. Weinmann, S. Dresen, A. Sclu eiber, M. Gergov, Development of a multi-target screening analysis for 301 drugs using a QTrap LC-MS-MS system and automated library searching. Rapid Commun. Mass Spectrom., 19 (2005) 1332. [Pg.358]

Kritzer JA, Luedtke NW, Harker EA, Schepartz A (2005) A rapid library screen for tailoring P peptide structure and function. J Am Chem Soc 127 14584—14585... [Pg.230]

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