Leucocytes, complement-mediated

Andreassen, J., Hoole, D. and Befus, D. (1990) Complement-mediated leucocyte adherence of newly excysted and 4-day-old Hymenolepis diminuta. International Journal for Parasitology 20, 905-911. 

CDS Defines MHC class I-restricted T cell subset present on NK cells CDIO Known to be common acute leukaemia antigen CDlla Known to be zn a chain of LFA-1 (leucocyte function antigen-1) present on several types of leucocyte and which mediates adhesion CDllc Known to be z complement receptor 4 a chain. 

The cytokines TNF-a and TNF- 3 are inflammatory mediators produced by macrophages and other cells in response to invasive stimuli such as bacterial LPS and endotoxins, antigen-antibody complexes, products of complement activation and cytokines. TNF activates leucocytes, increases neutrophil and monocyte adherence and migration and stimulates the synthesis of other pro-inflammatory cytokines. TNF-a is membrane-located and interacts with a PM-located receptor (GDI 20) leading to activation of caspases (cysteine proteases critically involved in cell death) and activation of PLA2. 

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