Leloir pathway, enzymes

The use of the non-Leloir pathway enzymes, which require sugar-l-phosphates as donors. 

It is clear, then, that perhaps no other group of compounds is as well suited to enzyme-based synthesis as is the carbohydrates. During the past several years, we have developed a range of enzyme-based syntheses for mono-, oligo-, and polysaccharides. This paper reviews some of our efforts on the use of aldolases and transketolase for monosaccharide synthesis, as well as the use of Leloir and non-Leloir pathway enzymes for glycosidic bond formation. 

Ross KL, Davis CN, Fridovich-Keil JL. Differential roles of the Leloir pathway enzymes and metabolites in defining galactose sensitivity in yeast. Mol Genet Metab 2004 83 103—116. 

Glycosyl transferases are essential enzymes for oligosaccharide biosynthesis. These enzymes can be classified as enzymes of the Leloir pathway and those of the non-Leloir pathway. The glycosyltransferases of the Leloir pathway are involved in the biosynthesis of most iV-linked... 

Inulin is not biosynthesised by a Leloir pathway involving a nucleotide mono- or diphospho sugar, but by transglyeosylating enzymes of GH 32 and GH 68 acting on sucrose. Only two enzymes are involved, a sucrose-sucrose 1-fructosyl transferase (1-SST), whieh produees the primer trisaccharide 1-kestose, and fructan 1-fruetosyltransferase (1-FFT), whieh exchanges... 

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