Lectins precursor

Protein 2 (P. vulgaris) oc-amylase inhibitor oc-chain (P. vulgaris) oc-amylase inhibitor like protein P. vulgaris) oc-amylase inhibitor 3 precursor (P. vulgaris) Probable lectin precursor (P. vulgaris)... 

Harley SM and Lord JM (1985). In vitro endopro-teolytic cleavage of castor bean lectin precursors. Plant Sci, 41, 111-116. 

A preproricin gene from Ricinus communis has been characterized by both cDNA [31] and genomic [150] cloning. Southern blot analysis has indicated that the Ricinus communis genome includes at least six lectin genes [150], In our laboratory we constructed a cDNA library using ripening castor bean endosperm poly(A)+ RNA which had been enriched for lectin precursor... 

In addition to the examples discussed above, these various reversed-phase HPLC mapping procedures have subsequently found numerous other advocates. Selected recent achievements include application to human hemoglobin variants 9a, 182, 185), the a- and j8-chains of rat hemoglobin 186), polypeptide hormones 9a, 99, 163), porcine C5a anaphylatoxin 187), Aplysia neuroactive polypeptide 188), ACTH/jS-lipotropin precursors 97, 99, 189, 190), oncoproteins 157), chick liver dihydrofolate reductase 191), limulin 192), ATP-citratelyase 193), spore-specific proteins 194), cAMP-dependent protein kinases (/95, 1%), interferons 197), complement components 9a, 198), aj-macroglobulin 198a), lectins 199), phycobiliproteins 200), bovine mitochondrial-F, ATPase 201), collagens, tubulins, and other structural proteins 9a, 202). 

As an additional source of complexity, the ricin gene is part of a multigene family within the castor bean plant that encodes for the production of pro-ricin (the natural ricin precursor), several apparently inactive polypeptides, and a well-studied, structurally related lectin called R. communis agglutinin I (RCA120) (Tregear and Roberts, 1992 Pinkerton et al., 1999 Helmy and Pieroni, 2000). 

Kini, R.M. (1996). Are C-type lectin-related proteins derived by proteolysis of metalloproteinase/disintegrin precursor proteins Toxicon. 54 1287-1294,... 

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