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Lead compounds rational drug design

Lead Compound Identification by Rational Drug Design... [Pg.117]

The recent emergence of combinatorial libraries made up of millions of chemically diverse compounds has revolutionized the drug discovery process. In contrast to the expectations of rational drug design, which enables compounds to be designed based on a detailed understanding of molecular interactions, chemical library diversity allows both direct de novo discovery of lead compounds, as well as enhancement of the activity of existing compounds. Combinatorial chemistry has proven to be a... [Pg.496]

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Compound, compounds design

Drug rational

Drugs lead compound

Lead compounds

Rational

Rational design

Rationalism

Rationally designed drug