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Lamotrigine pharmacokinetics

Garnett, W.R. (1997) Lamotrigine pharmacokinetics./Child Neurol 12 (Suppl 1) S10-S15. [Pg.324]

Gidal BE, Sheth R, Parnell J, et al. Evaluation of VPA dose and concentration effects on lamotrigine pharmacokinetics implications for conversion to lamotrigine monotherapy. Epilepsy Res 2003 57 85-93. [Pg.357]

Carbamazepine toxicity with lamotrigine pharmacokinetic or pharmacodynamic interaction Epilepsia... [Pg.301]

Gidal BE, Anderson GD, Rutecki PR, Shaw R, Lanning A. Lack of an effect of valproate concentration on lamotrigine pharmacokinetics in developmentaUy disabled patients with epilepsy. Epilepsy Res 2000 42(1) 23-31. [Pg.2001]

Posner, J., Holdich, T., and Crome, R, Comparison of lamotrigine pharmacokinetics in young and elderly healthy volunteers, J. Pharm. Med., 1 121-128, 1991. [Pg.262]

Coadministration with other hormonal contraceptive preparations or hormone replacement therapy Although the effect of other hormonal contraceptive preparations or replacement therapy on the pharmacokinetics of lamotrigine has not been evaluated, the effect may be similar to oral contraceptives. Therefore, similar adjustments to the dosage of lamotrigine may be needed. [Pg.1228]

Posner J, Cohen AF, Land G, et al. The pharmacokinetics of lamotrigine (BW430C) in healthy subjects with unconjugated hyperbilirubinaemia (Gilbert s syndrome). Br J Clin Pharmacol 1989 28(1) 117-120. [Pg.115]

Jawad S, Yuen WC, Peck AW, et al. Lamotrigine single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy. Epilepsy Res 1987 1(3) 194-201. [Pg.116]

Ebert U, Thong NQ, Oertel R, et al. Effects of rifampicin and cimetidine on pharmacokinetics and pharmacodynamics of lamotrigine in healthy subjects. Eur J Clin Pharmacol 2000 56(4) 299-304. [Pg.122]

Outlook Among the newer antiepileptics, gabapentin, oxycarbazepine, lamotrigine, and topiramate are now endorsed as primary monotherapeutics for both partial and generalized seizures. Their pharmacokinetic characteristics are generally more desirable than those of the older drugs. [Pg.192]

No likely pharmacokinetic interactions ot lamotrigine with lithium, atypical antipsychotics, or antidepressants... [Pg.238]

Ohman I, Vitois S, Tomson T. Lamotrigine in pregnancy Pharmacokinetics during delivery, in the neonate, and during lactation. Epilepsia 2000 41 709-13. [Pg.355]

In dogs concurrent administration of lamotrigine had no significant effect on the pharmacokinetics of carbamazepine or the plasma concentration ratio of carbamazepine epoxide to carbamazepine (97). [Pg.634]

Matar KM, Nicholls PJ, Bawazir SA, Al-Khamis KI, Al-Hassan MI. Effect of lamotrigine on the pharmacokinetics of carbamazepine and its active metabolite in dogs. Eur J Drug Metab Pharmacokinet 2001 26(3) 149-53. [Pg.637]

The effects of other antiepileptic drugs on the pharmacokinetics of lamotrigine have been studied in 62 patients with epilepsy (71). Carbamazepine, phenytoin, and phenobarbital, all enzjme inducers, increased the oral clearance of lamotrigine, individually by 58% and in combination by nearly 200%. [Pg.1998]

The effect of cimetidine on the pharmacokinetics of lamotrigine has been studied in 10 healthy men (73). Cimetidine had no effect on the pharmacokinetics of lamotrigine. [Pg.1998]

The effect of lamotrigine on steady-state lithium pharmacokinetics has been studied in 20 healthy adult men (75). Lamotrigine did not significantly change the pharmacokinetics of lithium. [Pg.1998]

Besag FM, Berry DJ, Pool F. Methsuximide lowers lamotrigine blood levels a pharmacokinetic antiepileptic drug interaction. Epilepsia 2000 41(5) 624-7. [Pg.2001]

Kanner AM, Frey M. Adding valproate to lamotrigine a study of their pharmacokinetic interaction. Neurology 2000 55(4) 588-91. [Pg.2001]

Cohen AF, Land GS, Breimer DD, Yuen WC, Winton C, Peck AW. Lamotrigine, a new anticonvulsant Pharmacokinetics in normal humans. CHn Pharmacol Ther 1987 42 535-41. [Pg.1281]

Della Paschoa OE, Hoogerkamp A, Edelbroek PM, Voskuyl RA, Danhof M. Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model. Epilepsy Res 2000 40 41-52. [Pg.76]

Drug Interactions. Lamotrigine does not inhibit or induce liver enzymes and has a low potential for pharmacokinetic interactions with other drugs. Lamotrigine does not interfere with oral contraceptives. [Pg.1039]

See other pages where Lamotrigine pharmacokinetics is mentioned: [Pg.132]    [Pg.1038]    [Pg.185]    [Pg.541]    [Pg.542]    [Pg.132]    [Pg.1038]    [Pg.185]    [Pg.541]    [Pg.542]    [Pg.339]    [Pg.1230]    [Pg.326]    [Pg.158]    [Pg.112]    [Pg.158]    [Pg.180]    [Pg.312]    [Pg.1667]    [Pg.2001]    [Pg.2097]    [Pg.2113]    [Pg.306]    [Pg.1039]    [Pg.1039]    [Pg.1043]   
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See also in sourсe #XX -- [ Pg.1030 , Pg.1038 , Pg.1274 , Pg.1275 , Pg.1277 ]

See also in sourсe #XX -- [ Pg.331 ]

See also in sourсe #XX -- [ Pg.221 ]



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