Lactose malabsorption

Johnson, J. D., Kretchmer, N. and Simoons, F. J. 1974. Lactose malabsorption its biology and history. In Advances in Pediatrics, Vol. 21.1. Schulman (Editor). Yearbook Medical Publishers, Chicago, pp. 197-237. 

Simoons, F. J. 1981. Geographic patterns of primary adult lactose malabsorption. A further interpretation of evidence from the Old World. In Lactose Digestion Clinical and Nutritional Implications. D.M. Paige and T.M. Bayless (Editors). Johns Hopkins University Press, Baltimore, pp. 23-48. 

Torun, B., Solomons, N. W. and Viteri, F. E. 1979. Lactose malabsorption and lactose intolerance Implications for general milk consumption. Archivos Latinoameri-canos de Nutrition 29, 445-494. 

Welsh, J. D. 1978. Diet therapy in adult lactose malabsorption Present practices. Am. J. Clin. Nutr. 31, 592-596. 

Savaiano, D. A., AbouElAnour, A., Smith, D. E., and Levitt, M. D. (1984). Lactose malabsorption from yogurt, pasteurized yogurt, sweet acidophilus milk, and cultured milk in lactase-deficient individuals. Am. J. Clin. Nutr. 40(6), 1219-1223. 

A common misconception is that lactose malabsorption and lactose intolerance symptoms are caused by an allergy to milk or other dairy products. Milk allergy is an immunologi-cally mediated reaction to milk proteins that may involve single systems (e.g., the gastrointestinal tract, skin, respiratory tract) or multiple... 

Di Stephano M, Veneto G, Malservisi S, et al. Lactose malabsorption and intolerance and peak bone mass. Gastroenterology 122 1793-1799, 2002. 

Saavedra JM, Perman JA Current concepts in lactose malabsorption and intolerance. A nnu Rev Nutr 9 475-502,1989. 

Lower doses of lactose produce fewer adverse effects, and lactose is better tolerated if taken with other foods. As a result, there is a significant population with lactose malabsorption who are still able to ingest normal amounts of lactose, such as that in milk, without the development of adverse side effects. " ... 

Gudmand-Hoyer E, Simony K. Individual sensitivity to lactose in lactose malabsorption. Am ] Dig Dis 1977 22(3) 177-181. 

Isokoski M, JussEa A, Sarna S. A simple screening method for lactose malabsorption. Gastroenterology 1972 62 28-32. 

Gundend-However E, Dahlquist A, Jarnum S (1970). The clinical significance of lactose malabsorption. Am J Gastroenterol 53 460-471. 

Lactase (intestinal) (EC 3.2.1.23). Lactase is present in infancy when it is required for digestion of lactose in the mother s milk. The enzyme then decreases markedly with age, so that abdominal pain and diarrhea result from drinking milk, due to failure to hydrolyse lactose in the intestinal mucosa and lactose malabsorption. Condition prevalent throughout the world, and hereditary persistence of high intestinal lactase activity prevails only on Northern European populations (and those derived from them) and certain Arab and Hamitic races. 

Table II. Effect of Daily Consumption of Pasteurized Whole Milk Containing 1. acidophilus on Lactose Malabsorption in Humans ...

Gilliland, S. E., and Kim, H. S., 1981, Influence of consuming milk containing cells of Lactobacillus acidophilus on lactose malabsorption in humans, Proc. Annu. Meet. Am. Soc. Microbiol. (Abstr.) 200. 

Nichols, M. A., 1978, Effect of a nonfermented milk inoculated with Lactobacillus acidophilus on lactose malabsorption, M. Sc. thesis, Oklahoma State University. 

Fernandes J, Vos CE, Douwes AC, Slotema E, Degenhart HJ. 1978. Respiratory hydrogen excretion as a parameter for lactose malabsorption in children. Am J Clin Nutr 31 597—602. 

Enzyme preparations from fungi (Aspergillus niger) or from yeast are used in the dairy industry to hydrolyze lactose. Immobilized enzymes are applied to produce milk suitable for people suffering from lactose malabsorption. Milk treated in this way can also be used to make products like skim milk concentrate or ice cream, thus avoiding interference by lactose due to its low solubility. 

Editorial. (1979). Lactose malabsorption and lactose intolerance. Lancet, 2, 831... 

A test which can be used in the diagnosis of lactose malabsorption, based on the fact that hydrogen is evolved when malab-sorbed carbohydrate is fermented by colonic bacteria. A proportion of the gas diffuses into the circulation and is carried to the lungs where it is exhaled. Gas chromatography can be used to measure the amount of hydrogen in the expired air. 

Gudmand-H0yer, E., 1971, Specific Lactose Malabsorption in Adults, Fadl s Forlag, Copenhagen. 

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