Lactose acid, conditions

Gluconic Acid. A process to convert lactose to gluconic acid and galactose has been reported (Zadow 1984). Lactose is treated under acidic conditions with bromine, and galactose is recovered from the product concentrate by crystallization. 

Lactosylurea. Lactosylurea is formed under acid conditions from lactose and urea (McAllan et al 1975) conversion of 75% of the lactose was achieved. Widell (1979) described a method for its preparation from whey and urea intended for feeding to ruminants. Ruminants can utilize nonprotein nitrogen compounds for protein synthesis, but urea itself can cause difficulties through too rapid decomposition to ammonia by the rumen enzymes. Lactosylurea appears to meet the requirements for satisfactory palatability, controlled nonprotein nitrogen release, and low toxicity. 

Some microorganisms effect the oxidation of oligosaccharides to glycosid-3-uloses this conversion has been reported for maltose, lactose, and their respective aldobionic acids. Conditions for the oxidation of sucrose by the action of Agrobacterium tumefaciens have been improved and optimized on a molar scale, so that 3-ketosucrose can be produced in 40% yield 449... 

ABSTRACT [2.23Cyclic Troger base 2 was synthesized by the condensation of 1,2-bis(4-aminophenyl)ethane with paraformaldehyde under acidic condition in 43.8% yield. [2.2]Cyclic Troger base 2 was separated into meso form and racemate by fractional crystallization or using HPLC. Resolution of the racemate into its optical antipodes by passing the racemate throu an activated D-(+)-lactose column was partially succeeded. 

In this example, the same starting trisaccharide 38, which has been developed by Turnbull et al. was used for botb reactions. For the photoaddition, the alkene groups were introduced to 38 by allylation under acidic conditions to give 39. Then, this compound was irradiated in the presence of hepta-O-acetyl-l-thio-p-lactose 40 and was easily deprotected to give the compound 41 in very good yields (73%) (Scheme 10). 

As stated previously, the native protein fractions of whey protein are implicated as offering the most health benefits associated with whey protein intake. Separating the fat, lactose, and minerals from these protein fractions without denaturing them was rather difficult and expensive until recently. One of the easiest ways to purify whey protein is to treat it with high heat and acid conditions to precipitate the proteins in a denatured form. Whey protein processed in this manner is typically referred to as hydrolyzed whey. The resulting small peptides are absorbed even faster than the larger native proteins present in the whey fraction. ... 

A remarkable inertness towards acylation is shown by the secondary hydroxyl group on C-3 in maltose, lactose, and their methyl j8-glycosides. Benzoylation of maltose with 10 molar equivalents of the acid chloride in pyridine gave122 the octabenzoate and the l,2,6,2, 3, 4, 6 -hepta-0-benzoyl derivative in the ratio of 5 6, and treatment of /3-maltose monohydrate with 8.8 molar equivalents of acetyl chloride in pyridine-toluene at 0° gave123 the 1,2,6,2, 3, 4, 6 -heptaacetate and the octaacetate in the ratio of 27 10. Under similar conditions of benzoylation, cellobiose was converted into its oc-... 

The derivative 90 was obtained by condensation of the purpurin-18-A-hexylimide-17-propionic acid with aminolactose heptaacetate in the presence of benzotriazol-l-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) followed by the deacetylation procedure. The lactose-photosensitiser conjugate linked by an ethylene moiety was also prepared by following a similar approach. The purpurin-18-methyl ester 81 was converted into /V-(3-iodobenzyl)/ /evo-purpurin-18-7V-hexylimide-17-propionic ester by hydrogenation over Pd/C followed by reaction with 3-iodo-benzylamine. Afterwards, the propargyllactose heptaacetate reacted with A-(3-iodobenzyl)rMeio-purpurin-18-A-hexylimide-l 7-propionic ester in the presence of tris(dibenzylidieneacetone)dipalladium(0) (Pd2-dba3) which, after deacetylation conditions, afforded the derivative 89 (Fig. 9).68... 

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