Aminocarboxylic acid lactams

It has become the custom to name linear aliphatic polyamides according to the number of carbon atoms of the diamine component (first named) and of the dicarboxylic acid. Thus, the condensation polymer from hexamethylenedi-amine and adipic acid is called polyamide-6,6 (or Nylon-6,6), while the corresponding polymer from hexamethylenediamine and sebacoic acid is called polyamide-6,10 (Nylon-6,10). Polyamides resulting from the polycondensation of an aminocarboxylic acid or from ring-opening polymerization of lactams are indicated by a single number thus polyamide-6 (Nylon-6) is the polymer from c-aminocaproic acid or from e-caprolactam. 

LACTAMIZATION REACTION OF AMINOCARBOXYLIC ACIDS CATALYZED BY (3,4,5-TRIFLUOROPHENYL)BORONIC ACID ... 

The reaction can be used to prepare five-, six-, and seven-membered lactams from y, S, and oj-aminocarboxylic acids. 

Also, p-lactams are obtained in high yield by the reaction of -aminocarboxylic acids with aldehydes and isocyanides. ... 

The formation of polymers from the monomers is known as polymerization reaction. When more than one basic unit forms the polymer, the process is also named copolymerization. The polymerization reactions can be classified into two main groups, addition polymerizations and condensation polymerizations (or polycondensations). For the addition polymerizations, the resulting polymer has the repeating unit with the same molecular formula as the monomer, and the molecular mass of the polymer is the sum of the molecular masses of all the monomer molecules. For the condensation polymerizations, the resulting polymer has the repeating unit with fewer atoms than that of the monomer or monomers, and the molecular mass of the polymer is less than the sum of molecular masses of the original monomer unit or units because small molecules are eliminated following this reaction. This classification is not adequate for the characterization of the polymer itself, because the same polymer can be formed by more than one type of reaction. For example, a polyamide can be formed by addition from a lactam or by condensation from an co-aminocarboxylic acid as shown below ... 

The lactamization of aminocarboxylic acids is the last step in the recent synthesis of aromatic-substituted 3-benzazepines.27 The appropriate phenethylamines (36, R1 = H, Me R2 = Ac, R3 = H) were converted by... 

Hydrogen chloride Aminocarboxylic acids from lactams... 

Ethyl chloro formate/triethylamine Lactams from aminocarboxylic acids s. 24, 513 s. a. F. Gatta and R. Landi Vittory, Farmaco, Ed. Sci., 25, 991 (1970)... 

Titanium tetraisopropoxide Lactams from aminocarboxylic acids... 

Sec. alcohols from ketones with formation of lactams from aminocarboxylic acid esters Stereospecific reduction... 

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