Lactamase Inhibitors as Antibacterial Agents

The design, synthesis, and biological properties of a new class of chiral boronic acids that effectively target two representative fi-lactamases found in nosocomial 

Several articles have appeared in recent literature on 1,2,3-triazole-based scaffolds as antimicrobial agents that are in hit stages of discovery [103-106]. 

A recent report [108] describes the synthesis of a small library of novel substituted 

The results of this study demonstrate the potential utility of scaffold hopping approach in designing new antitubercular analogs of carbazole with appended 

3- triazole fragment as potent antitubercular agents for further optimization. 

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Part A Application of Click Chemistry to Drug Discovery and Development 47 2.2.3.12 p-Lactamase Inhibitors as Antibacterial Agents... 

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