5-methyl-2-phenyl-l -

Imidazole, 1 -methyl-5-nitro-2-styryl-ozonolysis, 5, 437 Imidazole, l-methyl-2-phenyl- C NMR, 5, 354 Imidazole, l-methyl-4-phenyl- C NMR, 5, 355 Imidazole, 2-methyl-4-phenyl-acylation, 5, 402... 

Indolizine, hydroxy-conformations, 4, 451 GLC retention times, 4, 451 synthesis, 4, 121 tautomerism, 4, 198, 452 Indolizine, 2-hydroxy-synthesis, 4, 463 Indolizine, 8-hydroxy-conformation, 4, 452 Indolizine, 2-hydroxymethyl-synthesis, 4, 461 Indolizine, 3-hydroxymethyl-synthesis, 4, 461 Indolizine, 6-hydroxymethyl-synthesis, 4, 461 Indolizine, methyl-mass spectra, 4, 187, 450 NM 4, 448 Indolizine, 2-methyl-diazo coupling, 4, 454 mass spectra, 2, 529, 4, 450 nitration, 4, 50, 454 nitrosation, 4, 454 reaction with diaryl disulfide, 4, 460 reaction with nitroethane, 4, 460 Indolizine, 3-methyl-basicity, 4, 454 Indolizine, 5-methyl-acidity, 4, 461 synthesis, 4, 466 Indolizine, 6-methyl-mass spectra, 4, 450 Indolizine, l-methyl-2-phenyl-nitration, 4, 454 nitrosation, 4, 454, 455 Indolizine, 3-methyl-2-phenyl-reaction... 

This method provides a route to certain medium-ring sized enamines (106,107) not obtainable by other methods, l-Methyl-2-phenyl-l-azacyclo-hcpt-2-ene (124) can be prepared by the reaction of N-methylcaprolactam... 

As with the pyrroles, N-chloroamides have been widely employed in indole chlorination [66JOC2627 80H( 14)867 81JOC2054]. Chloroindolen-ines may be isolated under controlled conditions [80H( 14)867 81JOC2054], 2-Phenyl-, l-methyl-2-phenyl-and 3-methyl-2-phenyl-indoles were converted by 1-chloroisatin (NCI) into the 3-chloro derivatives... 

Analog erhalt man durch Reduktion mit Kaliumboranat aus l-Methyl-2-phenyl-indo-lyl-(3)-glyoxylsaure-dimethylamid 1-Methyl-2-phenyl-indolyl-(3)-glykolsaure-dimethyl-amid (F 137-1390)3. 

Jod-5-hydroxy-4-methoxy-phenyl)- -nitril 118 [l-Methyl-2-phenyl-indolyl-(3)]- -dimethylamid 321... 

Aus [l-Methyl-2-phenyl-2-(2-phenyl-hydrazino)-ethenyIamino]-malonsaure-methylester-nitril wird durch Kochen in Methanol in 68% Ausbeute l-Anilino-2-methoxycarbonyl-4-methyl-5-phenyl-imidazol erhalten328 ... 

Bei der Umsetzung von l-Methyl-2-phenyl-imidazol mit Chlor und Triethylamin in Tetrachlor-methan bei — 30° gelingt sogar die selektive Einfiihrung eines Chlor-Atoms in die 5-Position in 90% Ausbeute zu 5-Chlor-l-methyl-2-phenyl-imidazolbA1. 

Erhitzt man l-Methyl-2-phenyl-benzimidazol mit Natriumamid, so erhalt man unter Addition/C,C-Spal-tung und Eliminierung 2-Amino-l-methyl-benzimidazol (55%)433 ... 

Fluoro-l-methyl-2-phenyl-ethyl)-ElOa. 120 (Aziridin + HF) ElOb,. 259 (NH2 - F)... 

The refractive index of l-methyl-2-phenyl-A3-l,2,3-triazoline (2), which is obtained as a viscous liquid, has been measured (n26D = 1.5738).5... 

In nitric acid sulfuric acid, 3-methyl-1-phenylpyrazole yields the l-(4-nitrophenyl) derivative (96%), and 5-methyl-1-phenylpyrazole the l-(4-nitro-phenyl) derivative (98%). l-(2-Methylphenyl)- and 3,5-dimethyl-1-phenylpyrazole give low yields (up to 33%) of the 4-nitrophenyl products, but l-(2,6-dimethylphenyl) pyrazole gives l-(2,6-dimethyl-3-nitrophenyl) pyrazole (92%). The l-methyl-2-phenyl and 5-methyl-1-phenylpyrazolium cations are markedly less reactive than the 1-phenylpyrazolium cation, presumably because of steric hindrance to coplanarity of the rings. 

The assertion of W. L. F. Armarego [in Advances in Heterocyclic Chemistry (A. R. Katritzky, ed.), Vol. 1, pp. 282-283. Academic Press, New York, 1963], attempts made to prepare l,2-dimethyl-l,4-dihydroquinazo-lines from o-methylaminobenzyl chloride hydrochloride and acetonitrile in the presence of stannic chloride gave l,2-dimethyl-4(lH)-quinazolinone [M. Lora-Tamayo, R. Madronero, and G. G. Munoz, Ber. 94, 208 (1961)] , is mistaken. This type of reaction has permitted the preparation, for the first time, not only of l-methyl-2-phenyl-, l-methyl-2-(o-nitrophenyl)-, and l-methyl-2-(p-methoxyphenyl)-l,4-dihydroquinazolines, but also of 1,2-dimethyl-l,4-dihydroquinazoline. The stability of these compounds depends in a great measure on the substituent on position 2. Contrary to the statement of Armarego, the infrared spectrum of the tin complex has not been recorded by us. 

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