4- -l-butanol

CHa CHlCH CHO. Colourless lachrymatory liquid with a pungent odour. B.p. 104 "C. Manufactured by the thermal dehydration of aldol. May be oxidized to crotonic acid and reduced to crolonyl alcohol and 1-butanol oxidized by oxygen in the presence of VjOj to maleic anhydride. It is an intermediate in the production of l-butanol from ethanol. 

Nltropropane. The alkanolamines (qv), 2-amino-2-ethyl-l,3-propanediol and 2-amino-l-butanol, are produced by the two-step process described previously. 

Etliaiiolamiiies have been coiimieicially available for over 50 years and isopropanolaniines, for over 40 years. r( c-Butanolarnines have been prepared in research quantities, but are not available conmiercially. Piiniary butanolarnines, eg, 2-arnino-l-butanol [96-20-8] ate made by a different chemical route... 

Because they are similar, the aLkanolamines often can be used interchangeably. However, cost/perfomiance considerations generally dictate a best choice for specific appHcations. AMPD is manufactured in very low volumes for use as a reagent in certain medical diagnostic tests, although some is used in certain cosmetic products. 2-Ainino-1-butanol is used primarily as a taw material for the synthesis of ethambutol [74-55-5] an antituberculosis dmg. The first step in the synthesis of this dmg is the resolution of AB into its optical isomers because only (i)-2-amino-l-butanol, [5856-62-2] is utilized in this synthesis. 

Properties 1-Pentanol 2-Pentanol 3-Pentanol 2-Methyl-1 -butanol 3-Methyl-l -butanol 2-Methyl-2 -butanol 3-Methyl-2 -butanol 2,2-Dimeth5i -1-propanol... 

Amino alcohols can be resolved by a number of pathways including hydrolysis, esterification, and transesterification. For example, hydrolysis of Ai,0-diacet5l-2-amino-l-butanol with PPL followed by recrystallization results in (80a) with 95% ee (108). Hydrolysis of racemic acetates or butyrates of 2-[(aLkoxycarbonyl)amino]-l-aLkanols with PFL gives (R)-alcohol (81) with 95% ee (109). (3)-(81) can be obtained by transesterification of the racemic (81) with ethyl acetate which also serves as the reaction medium (109). 

Methyl-l-butanol [137-32-6 RS 34713-94-5 S(-)- 1565-80-6] M 88.2, b 130°(/ S), 128.6°(S), [a]p -5.8° (neat), d 0.809, n 1.4082. Refluxed with CaO, distd, refluxed with magnesium and again fractionally distd. A small sample of highly purified material was obtained by fractional crystn after conversion into a suitable ester such as the trinitrophthalate or the 3-nitrophthalate. The latter was converted to the cinchonine salt in acetone and recrystd from CHCI3 by adding pentane. The salt was saponified, extracted with ether, and fractionally distd. [Terry et al. J Chem Eng Data 5 403 7960.]... 

Chemical Designationis - Synonyms Fementation amyl alcohol Fusel oil Isobutylcarbinol Isopentyl alcohol 3-Methyl-l-butanol Potato-spirit oil Chemical Formula (CH3)2CHCH2CH20H. Observable Characteristics - Physical(asshipped) Liquid Color Colorless Odor. Mild odor alcoholic, non-residual. 

Compounds that have the sane relative configuration often have optical rotations of opposite sign. For exfflnple, treatment of (—)-2-methyl-l-butanol with hydrogen bromide converts it to (-l-)-l-bromo-2-methylbutane. 

Methyl-l-butanol Hydrogen l-Bromo-2-methylbutane Water... 

How would you prepare the following substances from l-butanol ... 

Methanol, ethanol, isopropylalcohol, n-propylalcohol, ferf-butyl alcohol, 2-butanol, 2-methyl-l-propanol, 1-butanol, 2-pentanol. 2-methyl-l-butanol, 1-pentanol... 

An example for a partially known ternary phase diagram is the sodium octane 1 -sulfonate/ 1-decanol/water system [61]. Figure 34 shows the isotropic areas L, and L2 for the water-rich surfactant phase with solubilized alcohol and for the solvent-rich surfactant phase with solubilized water, respectively. Furthermore, the lamellar neat phase D and the anisotropic hexagonal middle phase E are indicated (for systematics, cf. Ref. 62). For the quaternary sodium octane 1-sulfonate (A)/l-butanol (B)/n-tetradecane (0)/water (W) system, the tricritical point which characterizes the transition of three coexisting phases into one liquid phase is at 40.1°C A, 0.042 (mass parts) B, 0.958 (A + B = 56 wt %) O, 0.54 W, 0.46 [63]. For both the binary phase equilibrium dodecane... 

L9.67 (a) Write the structural formulas of diethyl ether and 1-butanol (note that they are isomers), (b) The boiling point of L-butanol is 117°C, higher than that of diethyl ether (35°C), yet the solubility of both compounds in water is about 8 g per 100 mL. Account for these observations. 

Epoxides give p-hydroxyalkyl carboxylates when treated with a carboxylic acid or a carboxylate ion and a suitable catalyst. Tetrahydrofiiran was opened to give O-benzoyl-4-iodo-l-butanol by treatment with benzoyl chloride and SmK. ... 

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