L-Ascorbic acid, properties

Physical Properties. Table 3 contains a summary of the physical properties of L-ascorbic acid. Properties relating to the stmcture of vitamin C have been reviewed and summarized (32). Stabilization of the molecule is a consequence of delocalization of the TT-electrons over the conjugated enediol system. The highly acidic nature of the H-atom on C-3 has been confirmed by neutron diffraction studies (23). 

More detailed accounts of particular enzyme reactions in the metabolism of ascorbic acid have appeared (K. Suzuki, Y. Mano, and N. Shimazono, Enzymatic formation of L-gulonolactone from n-glucuronolactone by rat liver microsomes. J. Biochem. (Tokyo) 47, 846-849, 1960 K. Suzuki, Y. Mano, and N. Shimazono, Conversion of L-gulonolactone to L-ascorbic acid. Properties of the microsomal enzyme in rat liver. J. Biochem. (Tokyo) 48, 313-315, 1960 J. D. Smiley, and G. Ashwell, Purification and properties of fi-L-hydroxy acid dehydrogenase. II. Isolation of fi-keto-L-gulonic acid, an intermediate in L-xyliJose biosynthesis. J. Biol. Chem. 236, 357-364, 1961). 

Lavrenov SN and Preobrazhenskaya MN, L-Ascorbic acid Properties and ways of modification. Pharmaceutical Chemistry Journal, 39(5) 251-264 (2005) Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39(5), 26-39 (2005). NB Cited Seib PA, Tolbert BM. Ascorbic acid Chemistry, metabolism and uses, Adv. in Chemistry Series, ACS, Washington DC (1982). 

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See also in sourсe #XX -- [ ]

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