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Keratan sulfate sulfation

As shown in Figure 48-8, the keratan sulfates consist of repeating Gal-GlcNAc disaccharide units containing sulfate attached to the 6 position of GlcNAc or occasionally of Gal. Type 1 is abundant in cornea, and type II is found along with chondroitin sulfate attached to hyaluronic acid in loose connective tissue. Types I and II have different attachments to protein (Figure 48—8). [Pg.545]

MIM 252940) Morquio A MPS IVA 6-sulfatase Galactosamine 6-sulfatase Keratan sulfate, chondroitin 6-sulfate... [Pg.546]

ECM, extracellular matrix HA, hyaluronic acid CS, chondroitin sulfate KS I, keratan sulfate I DS, dermatan sulfate HS, heparan sulfate. [Pg.548]

In various types of arthritis, proteoglycans may act as autoantigens, thus contributing to the pathologic feamres of these conditions. The amount of chondroitin sulfate in cartilage diminishes with age, whereas the amounts of keratan sulfate and hyaluronic acid increase. These changes may contribute to the development of osteoarthritis. Changes in the amounts of cer-... [Pg.548]

The major GAGs are hyaluronic acid, chondroitin 4- and 6-sulfates, keratan sulfates I and II, heparin, heparan sulfate, and dermatan sulfate. [Pg.554]

GM1-gangliosidosis, Morquio B GM1-ganglioside galactose-rich fragments of glycoproteins GM1 ganglioside Keratan sulfate... [Pg.686]

Core protein -------, chondroitin sulfate + + + + + + +, keratan sulfate xxxxx,... [Pg.36]

Keratan sulfate consists of a (l—>3)-0-/3-D-galactopyranosyl-(l— 4)-0-2-acetamido-2-deoxy-/3-D-glucopyranosy 1 repeating-unit containing 40% of galactosyl residues and >70% of 2-acetamido-2-deoxy-D-glucosyl residues esterified at C-6 by sulfate. [Pg.79]

Keratan sulfate (102-104), hen ovomucin (105), rat gastric mucins (106), porcine thyroglobulin (107) Recombinant tissue plasminogen activator expressed in mouse epithelial cells (108)... [Pg.329]

Keratan sulfate Galactose (Gal(Pl-4) GlcNAc6S (Pl-3).. Costal cartilage... [Pg.287]

See other pages where Keratan sulfate sulfation is mentioned: [Pg.542]    [Pg.127]    [Pg.478]    [Pg.486]    [Pg.486]    [Pg.486]    [Pg.236]    [Pg.290]    [Pg.291]    [Pg.383]    [Pg.542]    [Pg.542]    [Pg.543]    [Pg.543]    [Pg.544]    [Pg.544]    [Pg.544]    [Pg.545]    [Pg.546]    [Pg.547]    [Pg.117]    [Pg.254]    [Pg.53]    [Pg.687]    [Pg.502]    [Pg.79]    [Pg.329]    [Pg.330]    [Pg.331]    [Pg.286]    [Pg.292]    [Pg.301]   
See also in sourсe #XX -- [ Pg.215 ]



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