Karlin Group Tetradentate Model Compounds

This discussion of copper-containing enzymes has focused on structure and function information for Type I blue copper proteins azurin and plastocyanin, Type III hemocyanin, and Type II superoxide dismutase s structure and mechanism of activity. Information on spectral properties for some metalloproteins and their model compounds has been included in Tables 5.2, 5.3, and 5.7. One model system for Type I copper proteins39 and one for Type II centers40 have been discussed. Many others can be found in the literature. A more complete discussion, including mechanistic detail, about hemocyanin and tyrosinase model systems has been included. Models for the blue copper oxidases laccase and ascorbate oxidases have not been discussed. Students are referred to the references listed in the reference section for discussion of some other model systems. Many more are to be found in literature searches.50 

Frausto da Silva, J. R. R. Williams, R. J. R The Biological Chemistry of the Elements The Inorganic Chemistry of Life, Clarendon Press, New York, 1991, pp. 4CM-1, 389-399. 

Bio-Inorganic Chemistry, Ellis Horwood Limited, Halsted Press, New York, 1984. 

Inorganic Biochemistry, An Introduction, 2nd ed., Wiley-VCH, New York, 1997. 

Lippard, S. J. Berg, J. M. Principles of Bioinorganic Chemistry, University Science Books, Mill Valley, CA, 1994. 

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