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Journal of Pharmacology and

Lipinski, C.A. (2000) Drug-like Properties of Poor Solubility and Poor Permeability. Journal of Pharmacological and Toxicological Methods, 44(1), 235-249. [Pg.39]

Zhang, Y. and Wells, J., The effects of chronic caffeine administration on peripheral adenosine receptors, Journal of Pharmacology and Experimental Therapeutics, 254, 757, 1990. [Pg.252]

Rush, C., Sullivan, J. and Griffiths, R., Intravenous caffeine in stimulant drug abusers Subjective reports and physiological effects. Journal of Pharmacology and Experimental Therapeutics 273(1), 351-358, 1995. [Pg.295]

Lauver DA, Lockwood SF, and Lucchesi BR. 2005. Disodium disuccinate astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion. Journal of Pharmacology and Experimental Therapeutics 314(2) 686-692. [Pg.56]

Cunningham, M. 2000. Genomics and proteomics, the new millennium of drug discovery and development. Journal of Pharmacological and Toxicological Methods 44(1), 291-300. [Pg.103]

Zeng, H., Lozinskaya, I.M., Lin, Z., Willette, R.N., Brooks, D.P. and Xu, X. (2006) Mallotoxin is a novel human ether-a-go-go-related gene (hERG) potassium channel activator. The Journal of Pharmacology and Experimental Therapeutics, 319, 957-962. [Pg.78]

Nau, C., Seaver, M., Wang, S.Y. and Wang, G.K. (2000) Block of human heart hHl sodium channels by amitriptyline. The Journal of Pharmacology and Experimental Therapeutics, 292. 1015-1023. [Pg.82]

A. M. (2005) HERG-Lite a novel comprehensive high-throughput screen for drug-induced hERG risk. Journal of Pharmacological and Toxicological Methods, 52, 136-145. [Pg.82]

Anantharam, A., Markowitz, S.M. and Abbott, G.W. (2003) Pharmacogenetic considerations in diseases of cardiac ion channels. The Journal of Pharmacology and Experimental Therapeutics, 307, 831-838. [Pg.83]

Hamlin, R.L., Cruze, C.A., Mittelstadt, S. W., Kijtawomrat, A., Keene, B.W., Roche, B.M., Nakayama, T., Nakayama, H., Hamlin, D.M. and Arnold, T. (2004) Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc. Journal of Pharmacological and Toxicological Methods, 49, 15—23. [Pg.86]

Hanson, L.A., Bass, A.S., Gintant, G., Mittelstadt, S., Rampe, D. and Thomas, K. (2006) ILSI-HESI cardiovascular safety subcommittee initiative evaluation of three non-clinical models of QT prolongation. Journal of Pharmacological and Toxicological Methods, 54, 116—129. [Pg.86]

Gralinski, M.R. (2000) The assessment of potential for QT interval prolongation with new pharmaceuticals impact on drug development Journal of Pharmacological and Toxicological Methods, 43, 91-99. [Pg.87]

Ekins, S., Crumb, W.J., Sarazan, R.D., Wikel, J.H. and Wrighton, S.A. (2002) Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel. The Journal of Pharmacology and Experimental Therapeutics, 301, 427—434. [Pg.124]

H, X.Q., Bjorkman, A., Andersson, T.B., Ridderstrom, M. and Masimirembwa, C.M. (2002) Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2 C8 a new high affinity and turnover enzyme-specific probe substrate. Journal of Pharmacology and Experimental Therapeutics, 300 (2), 399-407. [Pg.233]

Thummel, K.E., Shen, D.D., Podoll,T.D., Kunze, K.L., Trager, W.F., Bacchi, C.E., Marsh, C.L., McVicar, J.P., Barr, D.M., Perkins, J.D., Carithers, R.L. (1994) Use of midazolam as a human cytochrome P450 3A probe. II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation. Journal of Pharmacology and Experimental Therapeutics, 271 (1), 557-566. [Pg.236]

Sutton, D., Butler, A.M., Nadin, L. and Murray, M. (1997) Role of CYP3A4 in human hepatic diltiazem N-demethylation inhibition of CYP3A4 activity by oxidized diltiazem metabolites. Journal of Pharmacology and Experimental Therapeutics, 282 (1), 294-300. [Pg.236]

Ernest, C.S., II, Hall, S.D. and Jones, D. R. (2005) Mechanism-based inactivation of CYP3A by HIV protease inhibitors. Journal of Pharmacology and Experimental Therapeutics, 312 (2), 583-591. [Pg.244]

B. K. (1967) Pharmacokinetics of paracetamol (acetaminophen) after intravenous and oral administration. British Journal of Pharmacology and Chemotherapy, 29, 150. [Pg.291]

C. M. Jr. (1972) Physiological disposition of fenprofen in man. III. Metabolism and protein binding of phenprofen. Journal of Pharmacology and Experimental Therapeutics, 183, 449. [Pg.291]

Sitar, D.S. and Thornhill, D.P. (1973) Methimazole absorption, metabolism and excretion in the albino rat. Journal of Pharmacology and Experimental Therapeutics, 184, 432. [Pg.291]

Mills, J.B., Rose, K.A., Sadagopan, N., Sahi, J. and de Morais, S.M. (2004) Induction of drug metabolism enzymes and MDR1 using a novel human hepatocyte cell line. The Journal of Pharmacology and Experimented Therapeutics, 309, 303-309. [Pg.315]

Egnell, A.-C., Houston, B. and Boyer, S. (2003) in vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine. The Journal of Pharmacology and Experimental Therapeutics, 305, 1251-1262. [Pg.333]

Gao, B., Hagenbuch, B., Kullak-Ublick, G.A., Benke, D., Aguzzi, A. and Meier, P. J. (2000) Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier. Journal of Pharmacology and Experimental Therapeutics, 294, 73-79. [Pg.356]


See other pages where Journal of Pharmacology and is mentioned: [Pg.295]    [Pg.194]    [Pg.283]    [Pg.82]    [Pg.82]    [Pg.85]    [Pg.87]    [Pg.104]    [Pg.107]    [Pg.140]    [Pg.153]    [Pg.153]    [Pg.232]    [Pg.245]    [Pg.275]    [Pg.276]    [Pg.276]    [Pg.276]    [Pg.313]    [Pg.314]    [Pg.334]    [Pg.357]   


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