Jaspis species

Japanese specimens of Jaspis sp. The jaspisins (520-521) inhibited hatching of sea urchin embryos and the narains (522-523) induced metamorphosis in ascidian larvae. Three 3,4-dihydroxystyrene sulfate dimers (524-526) were also isolated from the same Jaspis species [441]. 

The naturally occurring azepinone, bengamide Z 351, has been prepared in chiral form by Boeckman et al. <20020L2109>, and the related ester, bengamide Q 352 together with other bengamides, has been isolated from a Jaspis species <2001JOC1733>. 

Figure 19.40 Bengazoles ofJaspis and Pachastrissa. (Bengazole B is an inseparable mixture, 5/1, of esters /so-15 0 and ante/so-15 0. The Jaspis species were harvested in the Pacific and Pachystrissa at Djibouti in the Indian Ocean).

Groweiss, A., Newcomer, (.(., O Keefe, B.R., Blackman, A., and Boyd, M.R. (1999) Cytotoxic metabolites from an Australian collection of sponge Jaspis species. J. Nat. Prod., 62,1691-1693. 

Ohta, S., Kobayashi, H., and Ikegami, S. (1994a) Jaspisin, a novel styrylsulfate from the marine sponge Jaspis species. Biosci. Biotechnol. Biochem., 58,1752—1753. 

Triterpenoids are a minor group of sponge metabolites of these malabaricane/isomalabaricane triterpenoids, Fig. (21) are known from Jaspis and Stelletla sponge species. All of this group shows cytotoxicity and anti-HIV activity [136-139]. 

JASPIS — Hematite, Bloodstone. There is a green variety. The Jasp of the Germans is a stone of many species. Dioscorides enumerates seven ... 

Many chemical data relate to the species Jaspis stellifera which is now regarded as the species Rhabdastrella globostellata (see Systema Porifera, Hooper and Van Soest, 2002a). 

Jaspolides A-H, all isolated from an undetermined species of the genus Jaspis of Chinese origin, are triter-penes of isomalabaricane, similar to most of the above structures with the exception of jaspolides G and H, which may be derived by cycloaddition of the Diels-Alder type from stellettin A (Tang et al., 2006, 2007). 

Also isolated from species of the genus Jaspis, jaspisa-mides A-C are macrolactones whose ring consists of three... 

Wondonins A and B resemble the above structures but have an imidazole nucleus. They and were isolated from the association of two species Jaspis sp. and Poecillastra wondoensis mentioned above (Shin et al, 2001a). These are two epimers in 1 or 2 of the structure below in proportions similar to 1 to 3. Subsequently, new dimer and trimer analog derivatives were isolated from the same association between the two sponges (Chang et al, 2008). 

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