3-Methyl-6-isopropyl-phenol

Substance classes Properties — Effectiveness — Applications 5.2.2 Isopropyl-methyl-phenols CioH O M, 150 22... 

Table 45. Minimum Inhibition Concentrations (MIC) of Isopropyl-methyl-phenols in Nutrient Agar...

We note that the difference between the enthalpy of formation of the unsubstituted benzoquinone/nitrosophenol and that of its isopropyl methyl cymene-like disubstituted derivative is 146 kJmol, comparable to that of the corresponding hydrocarbons, benzene and its substituted counterpart as liquids, 127.0 1.2 kJmol, and as the corresponding phenols as solids, 144.4 9.6 kJmol . ... 

SYNS P-CYMEN-3-OL 3-p-CYMENOL 3-HYDRO-XY-p-CYMENE 3-HYDROXY-1-METHYL-4-ISOPROP-YLBENZENE ISOPROPYL CRESOL 6-ISOPROPYL-m-CRESOL 2-ISOPROPYL-5-METHYLPHENOL 1-METHYL-3-HYDROXY-4-ISOPROPYLBENZENE 5-METHYL-2-ISOPROPYL-1-PHENOL 5-METHYL-2-(l-METHYLETHYL)PHENOL THYME CAMPHOR THYMIC ACID m-THYMOL... 

METHYL-5-ISOPROPYLPHENOL see CCMOOO 5-METHYL-2-ISOPROPYL-1-PHENOL see TFX810 2-METHYL-3-(p-... 

Higher homologues of phenol include thymol (2-isopropyl-5-methyl phenol) and its isomer carvacrol (5-isopropyl-2-methyl-phenol)... 

Thymol, isopropyl meta-cresol, is a precursor of L-menthol. Meta-cresol with a purity of >98.5% must be used as the starting material for thymol production, because the isomer, 2-iso-propyl-4-methyl phenol derived from p-cresol is the main contaminant and cannot be easily separated from thymol. 

Phenol, 2-isopropyl-4-methyl- Phenol, 4-methyl-2-(1-methylethyl)-Empirical C10H14O... 

Synonyms Carbamic acid, methyl-, o-isopropy I phenyl ester Carbamic acid, methyl-, 2-(1-methylethyl) phenyl ester o-Cumenyl methylcarbamate Isoprocarb o-Isopropylphenol methylcarbamate o-lsopropylphenyl N-methylcarbamate Methyl carbamic acid-o-cumenyl ester 2-(1-Methylethyl) phenyl methylcarbamate MIPC Phenol, o-isopropyl-, methylcarbamate Phenol, 2-(1-methylethyl)-, methylcarbamate Empiricai C11H15NO2... 

The first successful industrial production of ( )-menthol was based on 3-methyl-phenol 2, which was transformed in two steps into 2-isopropyl-5-methyl cyclohexanol 4, i.e., into the menthol skeleton (Scheme 9.1) [10]. This structure has three stereogenic centres and therefore 2 = 8 stereoisomers. The inherent beauty of this process resides in the complete regioselectivity of isopropylation, controlled stereoelectrorrically by the two substituents oti the aromatic ring, and the high diastereoslectivity of hydrogenation to the all-trans product, one of three possible racemic diastereomers. 

METHOD 4 [115]-80% phenol in aqueous H2SO4 soiution of pH 3 is brought to 50 C. 30% H2O2 is then added causing an exothermic reaction and a temperature of 15 C over 3-4 minutes time. 6% aqueous H2SO3 is added after 4.5 minutes, the solution quickly cooled and extracted with isopropyl acetone (Strike would think that another solvent like methyl ethyl ketone could be used) to give 60% catechol. 

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